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OtherIMAGING

Evaluation of Patients with Head and Neck Cancer by Means of 99mTc-Glucarate

Juan P. Gambini, Margarita Nuñez, Pablo Cabral, Martín Lafferranderie, Javier Noble, Eduardo Corchs, Ricardo D'Albora, Eduardo Savio, Lucía Delgado and Omar Alonso
Journal of Nuclear Medicine Technology December 2009, 37 (4) 229-232; DOI: https://doi.org/10.2967/jnmt.109.062927
Juan P. Gambini
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Margarita Nuñez
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Pablo Cabral
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Martín Lafferranderie
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Javier Noble
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Eduardo Corchs
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Ricardo D'Albora
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Eduardo Savio
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Lucía Delgado
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Omar Alonso
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  • FIGURE 1. 
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    FIGURE 1. 

    A 62-y-old patient with larynx cancer. (A) Head and neck CT image of patient showing transaxial (left), sagittal (middle), and coronal (right) slices. (B) Head and neck 99mTc-glucarate SPECT image. (C) SPECT/CT fusion image. CT images show thickening of soft tissues of left side of subglottis with eccentricity and luminal stenosis. Fusion images show intense focal uptake in that region.

  • FIGURE 2. 
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    FIGURE 2. 

    A 65-y-old patient with clinical suspicion of local relapse from previously resected sclerosant basocellular epithelioma in right nasogenian fold. Patient underwent right maxillary antrectomy. (A) CT images show surgical sequel at roof of right maxillary sinus with mucosal thickening of cavity. (B and C) 99mTc-glucarate shows intense uptake (B) that in fusion images corresponded to location of pterigomaxilar fossa (C). Lesion was further confirmed as local relapse by biopsy.

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    TABLE 1

    Patient Characteristics

    Patient99mTc glucarate
    NumberPrimary tumor locationAge (y)SexpNStage after surgery of primary tumorSize (cm)*PathologyPrimary lesion or local relapseRegional node involvement
    1Oropharynx cancer55MN0IV5.5MDEC+−
    2Supraglottic tumor46MN2cIVA3.2MDEC++
    3Nasopharynx tumor61MN0IV4.6Undifferentiated carcinoma+−
    4Larynx cancer62MN0IV3.8WDEC+−
    5Glottic and supraglottic cancer80MN0III1.8WDEC+−
    6Carcinoma of right retromolar trigone57MN1IV6.2WDEC++
    7Tonsil cancer55MN1IVA3.8WDEC++
    8Larynx cancer66MN3IV3.7WDEC++
    9Right inferior maxillary tumor67MN0IV3.9WDEC+−
    10Right nasogenian fold tumor (postsurgery)65MLocal relapse?IV4.8Sclerosant basocellular epithelioma+−
    11Oropharynx tumor50MLocal relapse?IVA2.2PDEC+−
    • ↵* Greatest dimension.

    • MDEC = moderately differentiated epidermoid carcinoma; WDEC = well-differentiated epidermoid carcinoma; PDEC = poorly differentiated epidermoid carcinoma.

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Journal of Nuclear Medicine Technology: 37 (4)
Journal of Nuclear Medicine Technology
Vol. 37, Issue 4
December 2009
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Evaluation of Patients with Head and Neck Cancer by Means of 99mTc-Glucarate
Juan P. Gambini, Margarita Nuñez, Pablo Cabral, Martín Lafferranderie, Javier Noble, Eduardo Corchs, Ricardo D'Albora, Eduardo Savio, Lucía Delgado, Omar Alonso
Journal of Nuclear Medicine Technology Dec 2009, 37 (4) 229-232; DOI: 10.2967/jnmt.109.062927

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Evaluation of Patients with Head and Neck Cancer by Means of 99mTc-Glucarate
Juan P. Gambini, Margarita Nuñez, Pablo Cabral, Martín Lafferranderie, Javier Noble, Eduardo Corchs, Ricardo D'Albora, Eduardo Savio, Lucía Delgado, Omar Alonso
Journal of Nuclear Medicine Technology Dec 2009, 37 (4) 229-232; DOI: 10.2967/jnmt.109.062927
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