RT Journal Article SR Electronic T1 Evaluation of Patients with Head and Neck Cancer by Means of 99mTc-Glucarate JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP 229 OP 232 DO 10.2967/jnmt.109.062927 VO 37 IS 4 A1 Juan P. Gambini A1 Margarita Nuñez A1 Pablo Cabral A1 Martín Lafferranderie A1 Javier Noble A1 Eduardo Corchs A1 Ricardo D'Albora A1 Eduardo Savio A1 Lucía Delgado A1 Omar Alonso YR 2009 UL http://tech.snmjournals.org/content/37/4/229.abstract AB Preliminary findings have suggested that 99mTc-glucarate has tumor-seeking properties. The purpose of this study was to explore the potential of this tracer to evaluate malignant head and neck tumors by means of SPECT/CT software fusion imaging. Methods: Eleven male patients with advanced head and neck carcinoma were included in the study: 9 with locally advanced disease and 2 with clinical suspicion of local relapse. Scanning started 3–6 h after the injection of 1,110 MBq of 99mTc-glucarate. Planar and SPECT images of the head, neck, and thorax were acquired. Three-dimensional images were also coregistered with CT. Results: We found 99mTc-glucarate uptake in all suspected lesions. SPECT/CT fusion imaging was helpful in all cases for topographically localizing the tracer foci. Conclusion: 99mTc-glucarate can be considered a potential tracer for the evaluation of patients with head and neck tumors.