@article {Gambini229, author = {Juan P. Gambini and Margarita Nu{\~n}ez and Pablo Cabral and Mart{\'\i}n Lafferranderie and Javier Noble and Eduardo Corchs and Ricardo D{\textquoteright}Albora and Eduardo Savio and Luc{\'\i}a Delgado and Omar Alonso}, title = {Evaluation of Patients with Head and Neck Cancer by Means of 99mTc-Glucarate}, volume = {37}, number = {4}, pages = {229--232}, year = {2009}, doi = {10.2967/jnmt.109.062927}, publisher = {Society of Nuclear Medicine}, abstract = {Preliminary findings have suggested that 99mTc-glucarate has tumor-seeking properties. The purpose of this study was to explore the potential of this tracer to evaluate malignant head and neck tumors by means of SPECT/CT software fusion imaging. Methods: Eleven male patients with advanced head and neck carcinoma were included in the study: 9 with locally advanced disease and 2 with clinical suspicion of local relapse. Scanning started 3{\textendash}6 h after the injection of 1,110 MBq of 99mTc-glucarate. Planar and SPECT images of the head, neck, and thorax were acquired. Three-dimensional images were also coregistered with CT. Results: We found 99mTc-glucarate uptake in all suspected lesions. SPECT/CT fusion imaging was helpful in all cases for topographically localizing the tracer foci. Conclusion: 99mTc-glucarate can be considered a potential tracer for the evaluation of patients with head and neck tumors.}, issn = {0091-4916}, URL = {https://tech.snmjournals.org/content/37/4/229}, eprint = {https://tech.snmjournals.org/content/37/4/229.full.pdf}, journal = {Journal of Nuclear Medicine Technology} }