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Research ArticleImaging

U.S. Diagnostic Reference Levels and Achievable Administered Activities for Adult Renal Scintigraphy: An Analysis of the Intersocietal Accreditation Committee Nuclear Laboratories

Kevin P. Banks, Rutger S. Gunther, Mary B. Farrell, Justin G. Peacock, Maria Costello and Leonie L. Gordon
Journal of Nuclear Medicine Technology September 2021, 49 (3) 246-249; DOI: https://doi.org/10.2967/jnmt.120.261552
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Kevin P. Banks
1U.S. Army Brooke Army Medical Center, San Antonio, Texas;
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Rutger S. Gunther
1U.S. Army Brooke Army Medical Center, San Antonio, Texas;
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Mary B. Farrell
2Intersocietal Accreditation Commission, Ellicott City, Maryland; and
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Justin G. Peacock
1U.S. Army Brooke Army Medical Center, San Antonio, Texas;
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Maria Costello
2Intersocietal Accreditation Commission, Ellicott City, Maryland; and
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Leonie L. Gordon
3Department of Radiology, Medical University of South Carolina, Charleston, South Carolina
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  • FIGURE 1.
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    FIGURE 1.

    Distribution of 182 99mTc-MAG3 administered doses. Vertical axis is activity (MBq). Horizontal axis is number of doses. Most values are close to 370 MBq (10 mCi).

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    FIGURE 2.

    Distribution of 24 99mTc-DTPA administered doses. Vertical axis is activity (MBq). Horizontal axis is number of doses. Nearly all fall within 370- to 555-MBq (10–15 mCi) range.

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    FIGURE 3.

    Box-and-whisker plot comparing minimum, maximum, and quartiles for U.S. 99mTc-MAG3 and 99mTc-DTPA administered activities (MBq) along with outliers vs. DRLs from Japan and Europe (99mTc-MAG3 only).

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    TABLE 1

    Practice Characteristics of 108 Facilities Included in Intersocietal Accreditation Commission Accreditation Survey Period of October 2015 to December 2018

    Facility characteristicAverageMaximumMinimum
    No. of general NM exams per year*1,7639,07695
    No. of genitourinary NM exams per year866973
    Percentage of genitourinary NM of practice5%37%0.50%
    • *All non-PET, non-MPS diagnostic exams. MPS = myocardial perfusion scintigraphy.

    • NM = nuclear medicine.

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    TABLE 2

    Analysis of Administered Activities by Radiopharmaceutical

    Parameter99mTc-MAG3 (n = 182)99mTc-DTPA (n = 24)
    Minimum140.6 (3.8)206.1 (5.6)
    25th percentile303.4 (8.2)386.7 (10.5)
    50th percentile (AAA)370 (10)445.9 (12.1)
    75th percentile (DRL)392.2 (10.6)531.7 (14.4)
    Maximum588.3 (15.9)780.7 (21.1)
    • Data are megabecquerels followed by millicuries in parentheses.

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Journal of Nuclear Medicine Technology: 49 (3)
Journal of Nuclear Medicine Technology
Vol. 49, Issue 3
September 1, 2021
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U.S. Diagnostic Reference Levels and Achievable Administered Activities for Adult Renal Scintigraphy: An Analysis of the Intersocietal Accreditation Committee Nuclear Laboratories
Kevin P. Banks, Rutger S. Gunther, Mary B. Farrell, Justin G. Peacock, Maria Costello, Leonie L. Gordon
Journal of Nuclear Medicine Technology Sep 2021, 49 (3) 246-249; DOI: 10.2967/jnmt.120.261552
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Keywords

  • reference levels
  • renal scintigraphy
  • administered activity
  • 99mTc-MAG3
  • 99mTc-DTPA
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U.S. Diagnostic Reference Levels and Achievable Administered Activities for Adult Renal Scintigraphy: An Analysis of the Intersocietal Accreditation Committee Nuclear Laboratories
Kevin P. Banks, Rutger S. Gunther, Mary B. Farrell, Justin G. Peacock, Maria Costello, Leonie L. Gordon
Journal of Nuclear Medicine Technology Sep 2021, 49 (3) 246-249; DOI: 10.2967/jnmt.120.261552

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