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Research ArticleImaging

U.S. Diagnostic Reference Levels and Achievable Administered Activities for Adult Renal Scintigraphy: An Analysis of the Intersocietal Accreditation Committee Nuclear Laboratories

Kevin P. Banks, Rutger S. Gunther, Mary B. Farrell, Justin G. Peacock, Maria Costello and Leonie L. Gordon
Journal of Nuclear Medicine Technology September 2021, 49 (3) 246-249; DOI: https://doi.org/10.2967/jnmt.120.261552
Kevin P. Banks
1U.S. Army Brooke Army Medical Center, San Antonio, Texas;
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Rutger S. Gunther
1U.S. Army Brooke Army Medical Center, San Antonio, Texas;
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Mary B. Farrell
2Intersocietal Accreditation Commission, Ellicott City, Maryland; and
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Justin G. Peacock
1U.S. Army Brooke Army Medical Center, San Antonio, Texas;
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Maria Costello
2Intersocietal Accreditation Commission, Ellicott City, Maryland; and
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Leonie L. Gordon
3Department of Radiology, Medical University of South Carolina, Charleston, South Carolina
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Abstract

The goal of this work was to determine U.S. diagnostic reference levels (DRLs) and achievable administered activities (AAAs) for adult renal scintigraphy. Methods: Under an Institutional Review Board–approved protocol, data were collected from the Intersocietal Accreditation Commission during one 3-y accreditation cycle encompassing 110 facilities. Elements included radiopharmaceutical, administered activity, practice type, and examination volume. DRLs and AAAs were calculated and compared with non-U.S. values and societal recommendations as available. Results: Ninety-three facilities provided data on 99mTc-mercaptoacetyltriglycine (99mTc-MAG3), and 15 provided data on 99mTc-diethylenetriaminepentaacetic acid (99mTc-DTPA) for adult renal scintigraphy exams. Analysis demonstrated a DRL of 392.2 MBq (10.6 mCi) for 99mTc-MAG3 and 531.7 MBq (14.4 mCi) for 99mTc-DTPA, with an AAA of 370 MBq (10 mCi) for 99mTc-MAG3 and 445.9 MBq (12.1 mCi) for 99mTc-DTPA. Conclusion: The resultant calculated novel U.S. DRLs and AAAs may serve as benchmarks that nuclear medicine facilities may use to refine renal scintigraphy protocols, reduce patient doses, and potentially guide future societal guideline recommendations.

  • reference levels
  • renal scintigraphy
  • administered activity
  • 99mTc-MAG3
  • 99mTc-DTPA

Footnotes

  • Published online April 5, 2021.

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Journal of Nuclear Medicine Technology: 49 (3)
Journal of Nuclear Medicine Technology
Vol. 49, Issue 3
September 1, 2021
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U.S. Diagnostic Reference Levels and Achievable Administered Activities for Adult Renal Scintigraphy: An Analysis of the Intersocietal Accreditation Committee Nuclear Laboratories
Kevin P. Banks, Rutger S. Gunther, Mary B. Farrell, Justin G. Peacock, Maria Costello, Leonie L. Gordon
Journal of Nuclear Medicine Technology Sep 2021, 49 (3) 246-249; DOI: 10.2967/jnmt.120.261552

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U.S. Diagnostic Reference Levels and Achievable Administered Activities for Adult Renal Scintigraphy: An Analysis of the Intersocietal Accreditation Committee Nuclear Laboratories
Kevin P. Banks, Rutger S. Gunther, Mary B. Farrell, Justin G. Peacock, Maria Costello, Leonie L. Gordon
Journal of Nuclear Medicine Technology Sep 2021, 49 (3) 246-249; DOI: 10.2967/jnmt.120.261552
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Keywords

  • reference levels
  • renal scintigraphy
  • administered activity
  • 99mTc-MAG3
  • 99mTc-DTPA
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