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Journal of Nuclear Medicine Technology

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Idiopathic Hepatic Uptake of 99mTc Methylene Diphosphonate: A Case Report

Joanie MacDonald
Journal of Nuclear Medicine Technology March 2001, 29 (1) 32-36;
Joanie MacDonald
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    FIGURE 1.

    Initial bone scan on patient with diabetes mellitus, chronic pyelonephritis, and anemia.

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    FIGURE 2.

    Repeat bone scan performed approximately 60 h after the initial scan.

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    TABLE 1

    Laboratory Results

    Hospital Day
    AdmissionInitial bone scanRepeat bone scan
    AST (13-40 IU/L)56——
    ALP (43-122 IU/L)667——
    ALT (17-56 IU/L)28——
    Total biliribin (0-1.2 mg/dl)1——
    Albumin (3.5-5.0 gm/dl)3——
    BUN (5-25 mg/dl)44——
    Creatinine (0.5-1.5 mg/dl)4.4——
    Calcium (8.7-10.6 mg/dl)—6.96.4
    Phosphate (2.5-4.8 mg/dl)—10.76.8
    Magnesium (1.6-2.3 mg/dl)—2.6—
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    TABLE 2

    Causes of Abnormal Diffuse Hepatic Activity with Radiolabeled Diphosphonate

    Residual radioactivity from previous colloid scan
    Excessive aluminum ion from generator
    Excessive serum aluminum
    Excessive hydrolyzed-reduced 99mTc-MDP forming radiocolloids
    Injection of radioiodinated contrast medium following bone-agent injection
    Hepatic necrosis
    Metastatic calcification
    Amyloid
    Conditions of iron therapy and iron overload
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Journal of Nuclear Medicine Technology: 29 (1)
Journal of Nuclear Medicine Technology
Vol. 29, Issue 1
March 1, 2001
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Idiopathic Hepatic Uptake of 99mTc Methylene Diphosphonate: A Case Report
Joanie MacDonald
Journal of Nuclear Medicine Technology Mar 2001, 29 (1) 32-36;

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Idiopathic Hepatic Uptake of 99mTc Methylene Diphosphonate: A Case Report
Joanie MacDonald
Journal of Nuclear Medicine Technology Mar 2001, 29 (1) 32-36;
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