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Research ArticleSpecial Contribution

Nuclear Medicine and Molecular Imaging in Nodal Staging and Surveillance of Ocular Melanoma: Case Reports and Review of the Literature

Kenneth S. Zurcher, Odette M. Houghton, Joanne F. Shen, Mahesh Seetharam, Michael C. Roarke and Ming Yang
Journal of Nuclear Medicine Technology September 2021, 49 (3) 275-280; DOI: https://doi.org/10.2967/jnmt.120.260539
Kenneth S. Zurcher
1Department of Radiology, Mayo Clinic, Scottsdale, Arizona;
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Odette M. Houghton
2Department of Ophthalmology, Mayo Clinic, Scottsdale, Arizona; and
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Joanne F. Shen
2Department of Ophthalmology, Mayo Clinic, Scottsdale, Arizona; and
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Mahesh Seetharam
3Department of Hematology/Oncology, Mayo Clinic, Scottsdale, Arizona
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Michael C. Roarke
1Department of Radiology, Mayo Clinic, Scottsdale, Arizona;
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Ming Yang
1Department of Radiology, Mayo Clinic, Scottsdale, Arizona;
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Abstract

Ocular melanoma (OM) is a rare noncutaneous malignancy and consists of 2 different subtypes based on the anatomic location in the eye: uveal melanoma and conjunctival melanoma. Like cutaneous melanoma, OM benefits from nuclear medicine and molecular imaging in nodal staging and clinical management. Through the illustration of 2 distinctive cases, we aim to demonstrate the complementary roles of standard lymphoscintigraphy, advanced SPECT/CT, 18F-FDG PET/CT, and 18F-FDG PET/MRI in accurate nodal staging and surveillance of OM. We also review the epidemiology, existing staging guidelines, and management of uveal melanoma and conjunctival melanoma.

  • conjunctival melanoma
  • 18F-FDG/PET
  • lymphoscintigraphy
  • SPECT
  • uveal melanoma

Footnotes

  • Published online April 5, 2021.

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Journal of Nuclear Medicine Technology: 49 (3)
Journal of Nuclear Medicine Technology
Vol. 49, Issue 3
September 1, 2021
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Nuclear Medicine and Molecular Imaging in Nodal Staging and Surveillance of Ocular Melanoma: Case Reports and Review of the Literature
Kenneth S. Zurcher, Odette M. Houghton, Joanne F. Shen, Mahesh Seetharam, Michael C. Roarke, Ming Yang
Journal of Nuclear Medicine Technology Sep 2021, 49 (3) 275-280; DOI: 10.2967/jnmt.120.260539

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Nuclear Medicine and Molecular Imaging in Nodal Staging and Surveillance of Ocular Melanoma: Case Reports and Review of the Literature
Kenneth S. Zurcher, Odette M. Houghton, Joanne F. Shen, Mahesh Seetharam, Michael C. Roarke, Ming Yang
Journal of Nuclear Medicine Technology Sep 2021, 49 (3) 275-280; DOI: 10.2967/jnmt.120.260539
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Keywords

  • conjunctival melanoma
  • 18F-FDG/PET
  • lymphoscintigraphy
  • SPECT
  • uveal melanoma
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