PT - JOURNAL ARTICLE AU - Zurcher, Kenneth S. AU - Houghton, Odette M. AU - Shen, Joanne F. AU - Seetharam, Mahesh AU - Roarke, Michael C. AU - Yang, Ming TI - Nuclear Medicine and Molecular Imaging in Nodal Staging and Surveillance of Ocular Melanoma: Case Reports and Review of the Literature AID - 10.2967/jnmt.120.260539 DP - 2021 Sep 01 TA - Journal of Nuclear Medicine Technology PG - 275--280 VI - 49 IP - 3 4099 - http://tech.snmjournals.org/content/49/3/275.short 4100 - http://tech.snmjournals.org/content/49/3/275.full SO - J. Nucl. Med. Technol.2021 Sep 01; 49 AB - Ocular melanoma (OM) is a rare noncutaneous malignancy and consists of 2 different subtypes based on the anatomic location in the eye: uveal melanoma and conjunctival melanoma. Like cutaneous melanoma, OM benefits from nuclear medicine and molecular imaging in nodal staging and clinical management. Through the illustration of 2 distinctive cases, we aim to demonstrate the complementary roles of standard lymphoscintigraphy, advanced SPECT/CT, 18F-FDG PET/CT, and 18F-FDG PET/MRI in accurate nodal staging and surveillance of OM. We also review the epidemiology, existing staging guidelines, and management of uveal melanoma and conjunctival melanoma.