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Research ArticleImaging

Renal Cortical 68Ga-PSMA-11 PET and 99mTc-DMSA Images

Ismet Sarikaya, Ahmed Alqallaf and Ali Sarikaya
Journal of Nuclear Medicine Technology March 2021, 49 (1) 30-33; DOI: https://doi.org/10.2967/jnmt.120.248922
Ismet Sarikaya
1Department of Nuclear Medicine, Kuwait University Faculty of Medicine, Mubarak Al-Kabeer Hospital, Kuwait City, Kuwait
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Ahmed Alqallaf
2Department of Medicine, Division of Nephrology, Mubarak Al-Kabeer Hospital, Kuwait City, Kuwait; and
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Ali Sarikaya
3Department of Nuclear Medicine, Trakya University Faculty of Medicine, Edirne, Turkey
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    FIGURE 1.

    In patient with prostate cancer, 68Ga-PSMA-11 maximum-intensity-projection PET images (in high-intensity setting [left] and low-intensity setting [middle]) and selected coronal CT image (top right), PET image (middle right), and PET/CT fusion image (bottom right) 2 h (image could not be obtained at 1 h due to unexpected delay) after intravenous injection of 129.5 MBq (3.5 mCi) of 68Ga-PSMA-11 demonstrate physiologic high renal uptake and excellent distribution of activity in renal cortex. Approximately 1-cm cyst (arrow) is cause of cortical defect in upper pole of right kidney.

  • FIGURE 2.
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    FIGURE 2.

    99mTc-DMSA multiple planar and selected coronal SPECT images demonstrate slight cortical thinning and mildly reduced activity in upper pole of right kidney, without significant cortical defect. ANT = anterior; POST = posterior; LPO = left posterior oblique; RPO = right posterior oblique.

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    FIGURE 3.

    68Ga-PSMA-11 maximum-intensity-projection (MIP), PET, selected coronal PET/CT, fusion, transaxial and coronal AC PET, and coronal non-AC PET images with injected activity of 74 MBq (2 mCi) show slight cortical thinning and mildly reduced uptake in upper pole of right kidney, without significant defect. Images of renal cortex are of higher resolution with 68Ga-PSMA PET than with 99mTc-DMSA, as shown in Figure 2. Non-AC PET also provides good-quality images of kidneys.

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Journal of Nuclear Medicine Technology: 49 (1)
Journal of Nuclear Medicine Technology
Vol. 49, Issue 1
March 1, 2021
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Renal Cortical 68Ga-PSMA-11 PET and 99mTc-DMSA Images
Ismet Sarikaya, Ahmed Alqallaf, Ali Sarikaya
Journal of Nuclear Medicine Technology Mar 2021, 49 (1) 30-33; DOI: 10.2967/jnmt.120.248922

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Renal Cortical 68Ga-PSMA-11 PET and 99mTc-DMSA Images
Ismet Sarikaya, Ahmed Alqallaf, Ali Sarikaya
Journal of Nuclear Medicine Technology Mar 2021, 49 (1) 30-33; DOI: 10.2967/jnmt.120.248922
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Keywords

  • DMSA scan
  • 68Ga-PSMA
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