Occurrence of the Redifferentiation-Akin Phenomenon on 68Ga-DOTATATE PET/CT After CAPTEM Chemotherapy in Metastatic Neuroendocrine Tumors with Intermediate MIB1 Index: What Could Be the Molecular Explanation?

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FIGURE 1.
Tracer uptake (SUV_max, 11.47) in primary gastric mass on follow-up axial ⁶⁸Ga-DOTATATE PET/CT (top) and CT (bottom) images (left) compared with baseline images (right).
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FIGURE 2.
Krenning score 3 uptake in segment VII and VIII liver lesions on follow-up axial ⁶⁸Ga-DOTATATE PET/CT (top) and CT (bottom) images (left) compared with baseline images (right). Lesions are seen to be smaller on follow-up.
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FIGURE 3.
Baseline (bottom) and follow-up (top) maximum-intensity projection PET images (left) and coronal (middle) and sagittal (right) ⁶⁸Ga-DOTATATE PET/CT images. Tracer uptake is seen to be enhanced on follow-up.