PT  - JOURNAL ARTICLE
AU  - Priyanka Sharma
AU  - Sandip Basu
TI  - Occurrence of the Redifferentiation-Akin Phenomenon on <sup>68</sup>Ga-DOTATATE PET/CT After CAPTEM Chemotherapy in Metastatic Neuroendocrine Tumors with Intermediate MIB1 Index: What Could Be the Molecular Explanation?
AID  - 10.2967/jnmt.120.241539
DP  - 2020 Sep 01
TA  - Journal of Nuclear Medicine Technology
PG  - 290--291
VI  - 48
IP  - 3
4099  - http://tech.snmjournals.org/content/48/3/290.short
4100  - http://tech.snmjournals.org/content/48/3/290.full
SO  - J. Nucl. Med. Technol.2020 Sep 01; 48
AB  - In this report, we present the 68Ga-DOTATATE PET/CT images of a patient with a metastatic neuroendocrine tumor with an intermediate-grade/Ki-67 index who had minimal somatostatin receptor positivity on baseline 68Ga-DOTATATE PET/CT but high-grade positivity on somatostatin receptor imaging (Krenning score, III–IV) on follow-up scans after chemotherapy. This redifferentiation-akin phenomenon in intermediate-grade neuroendocrine tumors after chemotherapy can have potential implications for the feasibility of peptide receptor radionuclide therapy in this group of patients in the later phase of their disease course.