RT Journal Article
SR Electronic
T1 Occurrence of the Redifferentiation-Akin Phenomenon on <sup>68</sup>Ga-DOTATATE PET/CT After CAPTEM Chemotherapy in Metastatic Neuroendocrine Tumors with Intermediate MIB1 Index: What Could Be the Molecular Explanation?
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 290
OP 291
DO 10.2967/jnmt.120.241539
VO 48
IS 3
A1 Priyanka Sharma
A1 Sandip Basu
YR 2020
UL http://tech.snmjournals.org/content/48/3/290.abstract
AB In this report, we present the 68Ga-DOTATATE PET/CT images of a patient with a metastatic neuroendocrine tumor with an intermediate-grade/Ki-67 index who had minimal somatostatin receptor positivity on baseline 68Ga-DOTATATE PET/CT but high-grade positivity on somatostatin receptor imaging (Krenning score, III–IV) on follow-up scans after chemotherapy. This redifferentiation-akin phenomenon in intermediate-grade neuroendocrine tumors after chemotherapy can have potential implications for the feasibility of peptide receptor radionuclide therapy in this group of patients in the later phase of their disease course.