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The Use of 99mTc-HYNIC-TOC and 18F-FDG PET/CT in the Evaluation of Duodenal Neuroendocrine Tumor with Atypical and Extensive Metastasis Responding Dramatically to a Single Fraction of PRRT with 177Lu-DOTATATE

Sandip Basu and Amit Abhyankar
Journal of Nuclear Medicine Technology December 2014, 42 (4) 296-298; DOI: https://doi.org/10.2967/jnmt.114.139238

Article Figures & Data

Figures

  • FIGURE 1.
    FIGURE 1.

    99mTc-HYNIC-TOC planar (A) and SPECT (B) images demonstrating tracer uptake in residual primary tumor in duodenum (dotted arrow) and liver lesion (thin solid arrow) with fairly large area of photopenia suggesting necrosis. Diffuse uptake over axial and appendicular skeleton (with interspersed areas of focal uptake, particularly in left parietal bone) and intense bilateral uptake in breast nodules (thick solid arrows) indicate metastases from NET.

  • FIGURE 2.
    FIGURE 2.

    18F-FDG PET/CT demonstrating relatively intense uptake in duodenal primary tumor (dotted arrow), intense uptake bilaterally in metastatic breast nodules (solid arrows), low-grade 18F-FDG uptake in liver lesion, and no uptake in bone marrow.

  • FIGURE 3.
    FIGURE 3.

    Scan after 177Lu-DOTATATE therapy showing uptake pattern similar to that on pretreatment diagnostic 99mTc-HYNIC-TOC scintigraphy.

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