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Journal of Nuclear Medicine Technology

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Three-Dimensional Ordered-Subset Expectation Maximization Iterative Protocol for Evaluation of Left Ventricular Volumes and Function by Quantitative Gated SPECT: A Dynamic Phantom Study

Luca Ceriani, Teresa Ruberto, Angelika Bischof Delaloye, John O. Prior and Luca Giovanella
Journal of Nuclear Medicine Technology March 2010, 38 (1) 18-23; DOI: https://doi.org/10.2967/jnmt.109.070243
Luca Ceriani
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Teresa Ruberto
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Angelika Bischof Delaloye
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John O. Prior
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Luca Giovanella
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  • FIGURE 1. 
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    FIGURE 1. 

    Elements of cardiac phantom used in this study. (A) Torso-anthropomorphic phantom with dynamic insert simulating beating left ventricle. (B) External pump-control unit.

  • FIGURE 2. 
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    FIGURE 2. 

    End-diastolic (ED) and end-systolic (ES) representative tomographic slices reoriented along major cardiac axes (short axis [SA], vertical long axis [VLA], and horizontal long axis [HLA]) obtained from reconstruction of G-SPECT phantom study with 3D OSEM iterative protocol.

  • FIGURE 3. 
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    FIGURE 3. 

    Measured contrast and noise for various EM-equivalent iterations (I × S product) with fixed gaussian postprocessing filter FWHM value of 10 mm.

  • FIGURE 4. 
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    FIGURE 4. 

    Measured EDV, ESV, SV, and corresponding LVEF with various EM-equivalent iterations (I × S product) and fixed gaussian postprocessing filter FWHM value of 10 mm. Dotted lines represent actual values for EDV, ESV, SV, and LVEF of cardiac phantom.

  • FIGURE 5. 
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    FIGURE 5. 

    Measured LV volumes (EDV and ESV) with different gaussian postprocessing filter FWHM values for various EM-equivalent iterations (I × S product). Dotted lines represent actual values for EDV and ESV of cardiac phantom.

  • FIGURE 6. 
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    FIGURE 6. 

    Calculated LVEF with different gaussian postprocessing filter FWHM values for various EM-equivalent iterations (I × S product). Dotted line represents actual value for LVEF of cardiac phantom.

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Journal of Nuclear Medicine Technology: 38 (1)
Journal of Nuclear Medicine Technology
Vol. 38, Issue 1
March 2010
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Three-Dimensional Ordered-Subset Expectation Maximization Iterative Protocol for Evaluation of Left Ventricular Volumes and Function by Quantitative Gated SPECT: A Dynamic Phantom Study
Luca Ceriani, Teresa Ruberto, Angelika Bischof Delaloye, John O. Prior, Luca Giovanella
Journal of Nuclear Medicine Technology Mar 2010, 38 (1) 18-23; DOI: 10.2967/jnmt.109.070243

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Three-Dimensional Ordered-Subset Expectation Maximization Iterative Protocol for Evaluation of Left Ventricular Volumes and Function by Quantitative Gated SPECT: A Dynamic Phantom Study
Luca Ceriani, Teresa Ruberto, Angelika Bischof Delaloye, John O. Prior, Luca Giovanella
Journal of Nuclear Medicine Technology Mar 2010, 38 (1) 18-23; DOI: 10.2967/jnmt.109.070243
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Cited By...

  • Development of a 2-Layer Double-Pump Dynamic Cardiac Phantom
  • Influence of Reconstruction Parameters During Filtered Backprojection and Ordered-Subset Expectation Maximization in the Measurement of the Left-Ventricular Volumes and Function During Gated SPECT
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