¹⁸F-FDG PET/CT Versus ⁶⁸Ga-PSMA-11 PET/CT in Evaluation of Distant Metastatic Disease in Recurrent Renal Cell Carcinoma

Maximum-intensity-projection (MIP) image of ¹⁸F-FDG PET/CT (A) showed mildly ¹⁸F-FDG–avid soft-tissue mass (SUV_max, 6.40) measuring 10.1 × 6.3 × 9.5 cm in left chest wall, soft-tissue lesions in mediastinal region, and bilateral nodules in lung (dotted arrows in MIP images A and C). No abnormally increased ¹⁸F-FDG uptake was noted in fused coronal (B) or transaxial (E) images of neck region. ⁶⁸Ga-PSMA PET/CT showed intensely ⁶⁸Ga-PSMA–expressing left chest wall mass (SUV_max, 22.49; dotted arrow in C), mediastinal lesions, and bilateral nodules in lung (C). Additionally, intensely ⁶⁸Ga-PSMA–avid hypodense thyroid lesions were seen in fused coronal (D) and transaxial (F) images (solid arrows in D and F, and MIP images A and C).