PT  - JOURNAL ARTICLE
AU  - Parghane, Rahul V.
AU  - Basu, Sandip
TI  - <sup>18</sup>F-FDG PET/CT Versus <sup>68</sup>Ga-PSMA-11 PET/CT in Evaluation of Distant Metastatic Disease in Recurrent Renal Cell Carcinoma
AID  - 10.2967/jnmt.122.264014
DP  - 2023 Sep 01
TA  - Journal of Nuclear Medicine Technology
PG  - 261--262
VI  - 51
IP  - 3
4099  - http://tech.snmjournals.org/content/51/3/261.short
4100  - http://tech.snmjournals.org/content/51/3/261.full
SO  - J. Nucl. Med. Technol.2023 Sep 01; 51
AB  - Prostate-specific membrane antigen (PSMA) expression has been observed in the neovasculature of various malignancies. We present a case of metastatic renal cell carcinoma (RCC) with comparative 18F-FDG PET/CT and 68Ga-PSMA-11 imaging in which FDG PET/CT failed to detect metastatic thyroid disease and showed less 18F-FDG–concentrating lesions at other sites, whereas 68Ga-PSMA-11 PET/CT identified metastatic thyroid disease and demonstrated intensely 68Ga-PSMA-11–expressing distant metastatic lesions. 68Ga-PSMA-11 PET/CT may be considered a potentially useful imaging technique in RCC to detect metastasis and to guide the choice of specific treatments, such as PSMA-based radionuclide therapy in patients with recurrent metastatic RCC.