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Research ArticleRadiation Safety

Radiation Dose to Medical Staff from Administering 177Lu-PSMA-DKFZ-617 Therapy

Elahe Mahmoudi, Elahe Pirayesh, Mohammad Reza Deevband, Mahasti Amoui, Mohammadali Ghodsi Rad, Mehrdad Ghorbani Rad and Mahdi Ghorbani
Journal of Nuclear Medicine Technology September 2022, 50 (3) 269-273; DOI: https://doi.org/10.2967/jnmt.121.263135
Elahe Mahmoudi
1Biomedical Engineering and Medical Physics Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran;
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Elahe Pirayesh
2Nuclear Medicine Department, Shohadaye Tajrish Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; and
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Mohammad Reza Deevband
1Biomedical Engineering and Medical Physics Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran;
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Mahasti Amoui
2Nuclear Medicine Department, Shohadaye Tajrish Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; and
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Mohammadali Ghodsi Rad
2Nuclear Medicine Department, Shohadaye Tajrish Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; and
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Mehrdad Ghorbani Rad
3Nuclear Medicine Department, Shohadaye Tajrish Hospital, Tehran, Iran
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Mahdi Ghorbani
1Biomedical Engineering and Medical Physics Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran;
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Abstract

The number of radioligand therapy applications for metastatic castration-resistant prostate cancer has been continuously rising in most nuclear medicine departments in Iran, but to our knowledge, no one has studied the dose to staff who perform treatment procedures. The current study aimed to determine the external radiation dose received by staff who, using or not using a lead shield, treat patients with 177Lu-prostate-specific membrane antigen therapy. Methods: This study used a personal thermoluminescent digital survey meter to measure dose rates to staff at various distances from patients and determined the average time spent by staff at these distances. The deep-dose equivalent to staff was obtained. Results: The measured deep-dose equivalent to staff per patient was within the range of 1.8–5.2 mSv using a 2-mm lead shield and 3.3–8.1 mSv not using the shield. The shield markedly reduced the external dose to staff. Conclusion: The skill and accuracy of staff, and the speed with which they act, can directly affect their received dose.

  • nuclear medicine
  • 177Lu-PSMA-DKFZ-617
  • dose rate
  • prostate cancer
  • mean doses

Footnotes

  • Published online Dec. 6, 2021.

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Journal of Nuclear Medicine Technology: 50 (3)
Journal of Nuclear Medicine Technology
Vol. 50, Issue 3
September 1, 2022
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Radiation Dose to Medical Staff from Administering 177Lu-PSMA-DKFZ-617 Therapy
Elahe Mahmoudi, Elahe Pirayesh, Mohammad Reza Deevband, Mahasti Amoui, Mohammadali Ghodsi Rad, Mehrdad Ghorbani Rad, Mahdi Ghorbani
Journal of Nuclear Medicine Technology Sep 2022, 50 (3) 269-273; DOI: 10.2967/jnmt.121.263135

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Radiation Dose to Medical Staff from Administering 177Lu-PSMA-DKFZ-617 Therapy
Elahe Mahmoudi, Elahe Pirayesh, Mohammad Reza Deevband, Mahasti Amoui, Mohammadali Ghodsi Rad, Mehrdad Ghorbani Rad, Mahdi Ghorbani
Journal of Nuclear Medicine Technology Sep 2022, 50 (3) 269-273; DOI: 10.2967/jnmt.121.263135
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Keywords

  • nuclear medicine
  • 177Lu-PSMA-DKFZ-617
  • dose rate
  • prostate cancer
  • mean doses
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