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Research ArticleRadiation Safety

Diagnostic Reference Levels in PET Imaging at Chulabhorn Hospital, Thailand

Phornpailin Pairodsantikul, Paramest Wongsa, Chaluntorn Wongkri, Paphawarin Burasothikul, Attapon Jantarato and Chanisa Chotipanich
Journal of Nuclear Medicine Technology September 2024, 52 (3) 261-266; DOI: https://doi.org/10.2967/jnmt.124.267576
Phornpailin Pairodsantikul
1School of Radiological Technology, Faculty of Health Science Technology, HRH Princess Chulabhorn College of Medical Science, Bangkok, Thailand; and
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Paramest Wongsa
1School of Radiological Technology, Faculty of Health Science Technology, HRH Princess Chulabhorn College of Medical Science, Bangkok, Thailand; and
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Chaluntorn Wongkri
1School of Radiological Technology, Faculty of Health Science Technology, HRH Princess Chulabhorn College of Medical Science, Bangkok, Thailand; and
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Paphawarin Burasothikul
1School of Radiological Technology, Faculty of Health Science Technology, HRH Princess Chulabhorn College of Medical Science, Bangkok, Thailand; and
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Attapon Jantarato
2National Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, Thailand
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Chanisa Chotipanich
2National Cyclotron and PET Centre, Chulabhorn Hospital, Bangkok, Thailand
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Abstract

Diagnostic reference levels (DRLs) are an important tool for controlling radiation exposure and ensuring safety in medical applications. In Thailand, DRL data have been gathered and established for nuclear medicine diagnostics since 2021. However, there is a lack of information on PET imaging examinations. At the National Cyclotron and PET Scan Centre, Chulabhorn Hospital, radiopharmaceuticals are produced for medical imaging and research, and a wide range of PET/CT and PET/MRI examinations are performed. Our objective was to investigate the administered activity of radiopharmaceuticals in patients undergoing PET imaging, especially the existing data on DRLs in medical diagnostic imaging. Methods: This was a retrospective study on nuclear medicine patients at the National Cyclotron and PET Scan Centre in 2023. Statistical analysis, including the mean and the 75th percentile values, was conducted to determine DRLs according to the International Commission on Radiological Protection guidelines. Results: The center performed 8,711 PET/CT and PET/MRI studies with 13 protocols in 2023. The most commonly administered activity was 18F-FDG in oncology and neurology examinations, with DRLs of 186.11 and 136.16 MBq, respectively. These values were notably almost twice lower than several reports in other countries. Conclusion: There is a lack of comprehensive data on most DRLs for PET imaging at this center because of the nonwidespread use of several radiopharmaceuticals. However, the lower DRLs for 18F-FDG can highlight the need for ongoing investigation toward the establishment of local DRLs, as well as assurance on the safety and efficiency of radiation used in nuclear medicine.

  • diagnostic reference levels
  • administered activity
  • PET imaging

Footnotes

  • Published online Jun. 20, 2024.

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Journal of Nuclear Medicine Technology: 52 (3)
Journal of Nuclear Medicine Technology
Vol. 52, Issue 3
September 1, 2024
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Diagnostic Reference Levels in PET Imaging at Chulabhorn Hospital, Thailand
Phornpailin Pairodsantikul, Paramest Wongsa, Chaluntorn Wongkri, Paphawarin Burasothikul, Attapon Jantarato, Chanisa Chotipanich
Journal of Nuclear Medicine Technology Sep 2024, 52 (3) 261-266; DOI: 10.2967/jnmt.124.267576

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Diagnostic Reference Levels in PET Imaging at Chulabhorn Hospital, Thailand
Phornpailin Pairodsantikul, Paramest Wongsa, Chaluntorn Wongkri, Paphawarin Burasothikul, Attapon Jantarato, Chanisa Chotipanich
Journal of Nuclear Medicine Technology Sep 2024, 52 (3) 261-266; DOI: 10.2967/jnmt.124.267576
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  • Experiences of Nuclear Medicine Technologists Working in PET/CT Facilities in Gauteng Province, South Africa
  • Establishment of National Diagnostic Reference Levels for Administered Activity in Diagnostic Nuclear Medicine in Thailand
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Keywords

  • diagnostic reference levels
  • administered activity
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