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Research ArticleTeaching Case Study

Hybrid Imaging with SPECT/CT and SPECT/MRI in Hepatic Splenosis

Mehdi Djekidel and Mark Michalski
Journal of Nuclear Medicine Technology June 2022, 50 (2) 179-181; DOI: https://doi.org/10.2967/jnmt.121.263013
Mehdi Djekidel
1Division of Nuclear Medicine, Department of Radiology, Sidra Medicine, Doha, Qatar; and
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Mark Michalski
2MGH and BWH Center for Clinical Data Science, Boston, Massachusetts
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  • FIGURE 1.
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    FIGURE 1.

    (A) Single-phase CT scan obtained at different hospital does not demonstrate typical arterial enhancement (arrow). (B) Ultrasound image shows hyperechoic mass (arrow). Mass would typically be hypoechoic.

  • FIGURE 2.
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    FIGURE 2.

    Axial MR images of area of lesion (arrows). (A) T1-weighted fat-saturated volumetric interpolated breath-hold examination (VIBE) sequence shows typical hypointensity. (B) Arterial-phase T1-weighted VIBE sequence shows no uptake of gadoxetate disodium (Eovist; Bayer). (C) T2-weighted sequence shows typical hyperintensity. (D) Portal venous–phase T1-weighted VIBE sequence shows no gadoxetate disodium uptake.

  • FIGURE 3.
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    FIGURE 3.

    18F-FDG PET/CT images of lesion and lymphadenopathy (arrows). (A) Axial (left) and coronal (right) images show liver lesion exhibiting glucose metabolic activity similar to that of surrounding normal parenchyma. (B) Coronal (bottom left and right) images show widespread 18F-FDG–avid lymphadenopathy.

  • FIGURE 4.
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    FIGURE 4.

    (A and B) 99mTc-labeled heat-damaged red blood cell images show increased uptake in hepatic (A) and left flank (B) splenule. (C and D) Coronal T1-weighted MR (C) and SPECT/MR (D) images show intrahepatic splenosis in unusual location (arrows).

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Journal of Nuclear Medicine Technology: 50 (2)
Journal of Nuclear Medicine Technology
Vol. 50, Issue 2
June 1, 2022
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Hybrid Imaging with SPECT/CT and SPECT/MRI in Hepatic Splenosis
Mehdi Djekidel, Mark Michalski
Journal of Nuclear Medicine Technology Jun 2022, 50 (2) 179-181; DOI: 10.2967/jnmt.121.263013

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Hybrid Imaging with SPECT/CT and SPECT/MRI in Hepatic Splenosis
Mehdi Djekidel, Mark Michalski
Journal of Nuclear Medicine Technology Jun 2022, 50 (2) 179-181; DOI: 10.2967/jnmt.121.263013
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  • Utility of 18F-FDG PET/CT in Assessment of Disease Extent and Response to Treatment in Xanthoma Disseminatum
  • The Role of [99mTc]Tc-Sestamibi in Functional Imaging of the Iodine-Loaded Thyroid Gland
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Keywords

  • oncology
  • hepatic splenosis
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  • SPECT/CT
  • SPECT/MRI
  • sulfur colloid
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