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Journal of Nuclear Medicine Technology

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Research ArticleTeaching Case Studies

Follicular Thyroid Carcinoma with Unusual Radioiodine-Refractory Breast Metastasis Mimicking Primary Breast Malignancy

Tarun Kumar Jain, Venkata Subramanian Krishnaraju, Bhagwant Rai Mittal, Ashwani Sood, Rajender Kumar, Rashi Garg and Sunil Kumar
Journal of Nuclear Medicine Technology September 2021, 49 (3) 288-289; DOI: https://doi.org/10.2967/jnmt.120.259259
Tarun Kumar Jain
1Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India; and
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Venkata Subramanian Krishnaraju
1Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India; and
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Bhagwant Rai Mittal
1Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India; and
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Ashwani Sood
1Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India; and
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Rajender Kumar
1Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India; and
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Rashi Garg
2Cytopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
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Sunil Kumar
1Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India; and
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    FIGURE 1.

    Whole-body radioiodine planar (A), transaxial SPECT/CT (B, D, F, and H), and CT (C, E, G, and I) images showing iodine-avid residual tissue in thyroid bed (B and C, solid arrows), multiple cervical and mediastinal lymph nodes (D and E, arrows), bilateral lung nodules (F and G, dashed arrows), and a few non–tracer-avid cervical lymph nodes (B and C, dashed arrows), right-breast lesions (F and G, solid arrows), and skeletal lesions (H and I, arrows).

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    FIGURE 2.

    Maximum-intensity-projection PET image (A) and transaxial PET/CT images (B, C, and D) showing 18F-FDG–avid lesions in right breast (B, arrow; SUVmax, 3.6), spleen (C, arrow), and D12 vertebra (D, arrow) (nonavid on whole-body iodine scan).

  • FIGURE 3.
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    FIGURE 3.

    Photomicrograph of sample from fine-needle aspiration of right-breast lesion showing monomorphic tumor cells arranged in microfollicles (May-Grünwald-Giemsa stain, ×100; arrow), suggestive of metastatic follicular carcinoma from thyroid.

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Journal of Nuclear Medicine Technology: 49 (3)
Journal of Nuclear Medicine Technology
Vol. 49, Issue 3
September 1, 2021
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Follicular Thyroid Carcinoma with Unusual Radioiodine-Refractory Breast Metastasis Mimicking Primary Breast Malignancy
Tarun Kumar Jain, Venkata Subramanian Krishnaraju, Bhagwant Rai Mittal, Ashwani Sood, Rajender Kumar, Rashi Garg, Sunil Kumar
Journal of Nuclear Medicine Technology Sep 2021, 49 (3) 288-289; DOI: 10.2967/jnmt.120.259259

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Follicular Thyroid Carcinoma with Unusual Radioiodine-Refractory Breast Metastasis Mimicking Primary Breast Malignancy
Tarun Kumar Jain, Venkata Subramanian Krishnaraju, Bhagwant Rai Mittal, Ashwani Sood, Rajender Kumar, Rashi Garg, Sunil Kumar
Journal of Nuclear Medicine Technology Sep 2021, 49 (3) 288-289; DOI: 10.2967/jnmt.120.259259
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Keywords

  • follicular thyroid carcinoma
  • iodine scan
  • 18F-FDG
  • PET/CT
  • breast metastasis
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