PT  - JOURNAL ARTICLE
AU  - Tarun Kumar Jain
AU  - Venkata Subramanian Krishnaraju
AU  - Bhagwant Rai Mittal
AU  - Ashwani Sood
AU  - Rajender Kumar
AU  - Rashi Garg
AU  - Sunil Kumar
TI  - Follicular Thyroid Carcinoma with Unusual Radioiodine-Refractory Breast Metastasis Mimicking Primary Breast Malignancy
AID  - 10.2967/jnmt.120.259259
DP  - 2021 Sep 01
TA  - Journal of Nuclear Medicine Technology
PG  - 288--289
VI  - 49
IP  - 3
4099  - http://tech.snmjournals.org/content/49/3/288.short
4100  - http://tech.snmjournals.org/content/49/3/288.full
SO  - J. Nucl. Med. Technol.2021 Sep 01; 49
AB  - The breast is an unusual site for metastasis from malignant tumors, although it may be the first manifestation of an extramammary primary malignancy typically arising in the lung, skin (melanoma), ovary, or lymph nodes (lymphoma). Breast metastasis from thyroid carcinoma is extremely rare and may take years to develop, as differentiated thyroid carcinoma is usually indolent and slow-growing and metastasizes to the lymph nodes, lungs, and bones. Here, we present the case of a middle-aged woman (after subtotal thyroidectomy for multinodular goiter 24 y previously) showing discordant 18F-FDG and iodine avidity in proven metastatic disease involving the lymph nodes, bones, spleen, and breast on whole-body 131I and 18F-FDG scans due to tumor heterogeneity.