Effect of Diet on Physiologic Bowel 18F-FDG Uptake

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FIGURE 1.
Grading bowel uptake by comparing it with that of liver as severe (more than liver) (A), moderate (equal to liver) (B), or mild (less than liver) (C).

TABLE 1

Demographics and Baseline Characteristics of Subjects

Variable	RD	LCHFD	P
Age (y)	47.73 ± 15.73	47.46 ± 15.59	0.8
Weight (kg)	72.57 ± 14.85	70.57 ± 14.16	0.6
Height (cm)	167.90 ± 9.79	166.67 ± 9.66	0.9
Systolic blood pressure (mm Hg)	119.95 ± 15.68	116.93 ± 13.94	0.7
Diastolic blood pressure (mm Hg)	79.04 ± 8.81	77.51 ± 7.80	0.3
Fasting blood sugar (mg/dL)	95.21 ± 18.73	93.69 ± 17.13	0.6
Heart rate (bpm)	80.35 ± 9.24	80.67 ± 9.06	0.5
¹⁸F-FDG injected dose (MBq [mCi])	390.72 ± 67.34 (10.56 ± 1.82)	394.79 ± 61.42 (10.67 ± 1.66)	0.6
Sex (n)			0.7
Male	55 (51.4%)	52 (48.6%)
Female	52 (48.6%)	55 (51.4%)

TABLE 2

¹⁸F-FDG Distribution Patterns in Bowel Regions

	¹⁸F-FDG uptake
	None		Mild		Moderate		Severe
Pattern of ¹⁸F-FDG distribution	RD	LCHFD	RD	LCHFD	RD	LCHFD	RD	LCHFD	P
Cecum	0	0	83 (77.57)	84 (78.50)	1 (0.93)	0	23 (21.50)	23 (21.50)	0.6
Ascending colon	66 (61.68)	72 (67.29)	17 (15.89)	23 (21.50)	19 (17.76)	9 (8.41)	5 (4.67)	3 (2.80)	0.1
Transverse colon	89 (83.18)	97 (90.65)	9 (8.41)	7 (6.54)	8 (7.48)	3 (2.80)	1 (0.93)	0	0.2
Descending colon	9 (8.41)	31 (28.97)	59 (55.14)	53 (49.53)	29 (27.10)	18 (16.82)	10 (9.34)	5 (4.67)	<0.001
Hepatic flexure	0	0	92 (85.98)	92 (85.98)	0	1 (0.93)	15 (14.02)	14 (13.08)	0.5
Splenic flexure	0	1 (0.93)	90 (84.11)	87 (81.31)	0	0	17 (15.89)	19 (17.76)	0.5
Small intestine	18 (16.82)	28 (26.17)	71 (66.36)	73 (68.22)	18 (16.82)	5 (4.67)	0	1 (0.93)	0.01

TABLE 3

¹⁸F-FDG Distribution Patterns in Bowel Regions after Exclusion of Patients with History of Colon Cancer

	¹⁸F-FDG uptake
	None		Mild		Moderate		Severe
Pattern of ¹⁸F-FDG distribution	RD	LCHFD	RD	LCHFD	RD	LCHFD	RD	LCHFD	P
Cecum	0	0	74 (76.29)	66 (79.52)	1 (1.03)	0	22 (22.68)	17 (20.48)	0.6
Ascending colon	61 (62.89)	56 (67.47)	14 (14.43)	18 (21.69)	17 (17.53)	6 (7.23)	5 (5.15)	3 (3.61)	0.1
Transverse colon	80 (82.47)	76 (91.57)	8 (8.25)	5 (6.02)	8 (8.25)	2 (2.41)	1 (1.03)	0	0.2
Descending colon	8 (8.25)	24 (28.92)	53 (54.64)	44 (53.01)	26 (26.80)	11 (13.25)	10 (10.31)	4 (4.82)	<0.001
Hepatic flexure	0	0	82 (84.54)	73 (87.95)	0	1 (1.20)	15 (15.46)	9 (10.84)	0.37
Splenic flexure	0	1 (1.20)	81 (83.51)	68 (81.93)	0	0	16 (16.49)	14 (16.87)	0.5
Small intestine	17 (17.53)	22 (26.51)	62 (63.92)	56 (67.47)	18 (18.56)	4 (4.82)	0	1 (1.20)	0.02