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Review ArticleTeaching Case Studies

Pitfall of 18F-FDG PET/CT in Characterization of Relapsed Multisystem Lymphomatoid Granulomatosis

Kelly Tung, Allison C. Rosenthal, Fiona E. Craig, Jonathan B. Ashman and Ming Yang
Journal of Nuclear Medicine Technology December 2018, 46 (4) 396-397; DOI: https://doi.org/10.2967/jnmt.118.212274
Kelly Tung
1Department of Radiology, Mayo Clinic Arizona, Scottsdale, Arizona
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Allison C. Rosenthal
2Department of Hematology/Oncology, Mayo Clinic Arizona, Scottsdale, Arizona
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Fiona E. Craig
3Department of Laboratory Medicine and Pathology, Mayo Clinic Arizona, Scottsdale, Arizona; and
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Jonathan B. Ashman
4Department of Radiation Oncology, Mayo Clinic Arizona, Scottsdale, Arizona
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Ming Yang
1Department of Radiology, Mayo Clinic Arizona, Scottsdale, Arizona
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  • FIGURE 1.
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    FIGURE 1.

    (A) Staging 18F-FDG PET/CT showed multiple hypermetabolic lung lesions (arrow). (B) After 6 cycles of R-CHOP therapy, all lesions resolved. (C) Seven months later, restaging 18F-FDG PET/CT showed multiple subcutaneous hypermetabolic lesions (white arrows) and a left lung hypermetabolic nodule (black arrow).

  • FIGURE 2.
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    FIGURE 2.

    Contrast-enhanced brain MRI showed enhancing lesion (arrows) involving left trigeminal nerve (A), which was 18F-FDG avid (SUVmax, 6.3) on restaging 18F-FDG PET (B) and PET/MRI (C).

  • FIGURE 3.
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    FIGURE 3.

    Restaging 18F-FDG PET/CT showed 18F-FDG avid subcutaneous nodule (arrows) with SUVmax of 10.3 on right anterior chest wall. Excisional biopsy confirmed grade 1 cutaneous lymphomatoid granulomatosis.

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Journal of Nuclear Medicine Technology: 46 (4)
Journal of Nuclear Medicine Technology
Vol. 46, Issue 4
December 1, 2018
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Pitfall of 18F-FDG PET/CT in Characterization of Relapsed Multisystem Lymphomatoid Granulomatosis
Kelly Tung, Allison C. Rosenthal, Fiona E. Craig, Jonathan B. Ashman, Ming Yang
Journal of Nuclear Medicine Technology Dec 2018, 46 (4) 396-397; DOI: 10.2967/jnmt.118.212274

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Pitfall of 18F-FDG PET/CT in Characterization of Relapsed Multisystem Lymphomatoid Granulomatosis
Kelly Tung, Allison C. Rosenthal, Fiona E. Craig, Jonathan B. Ashman, Ming Yang
Journal of Nuclear Medicine Technology Dec 2018, 46 (4) 396-397; DOI: 10.2967/jnmt.118.212274
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Keywords

  • hematology
  • lymphoma
  • PET/CT
  • 18F-FDG
  • Lung
  • lymphomatoid granulomatosis
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