PT - JOURNAL ARTICLE AU - Tung, Kelly AU - Rosenthal, Allison C. AU - Craig, Fiona E. AU - Ashman, Jonathan B. AU - Yang, Ming TI - Pitfall of <sup>18</sup>F-FDG PET/CT in Characterization of Relapsed Multisystem Lymphomatoid Granulomatosis AID - 10.2967/jnmt.118.212274 DP - 2018 Dec 01 TA - Journal of Nuclear Medicine Technology PG - 396--397 VI - 46 IP - 4 4099 - http://tech.snmjournals.org/content/46/4/396.short 4100 - http://tech.snmjournals.org/content/46/4/396.full SO - J. Nucl. Med. Technol.2018 Dec 01; 46 AB - We present serial 18F-FDG PET/CT findings in a case of grade 3 pulmonary lymphomatoid granulomatosis positive for the Epstein–Barr virus. The patient experienced a transient complete response to R-CHOP chemotherapy and subsequent multisystem recurrence, predominately involving the subcutaneous region of the torso on 18F-FDG PET/CT. Biopsy of the most hypermetabolic subcutaneous lesion demonstrated grade 1 cutaneous lymphomatoid granulomatosis negative for the Epstein–Barr virus. This report highlights the role of 18F-FDG PET/CT in characterizing and monitoring disease progression and regression, as well as the limitations of 18F-FDG PET/CT in accurate grading of multisystem recurrence, given the diversity of clinical and histopathologic features of lymphomatoid granulomatosis.