RT Journal Article
SR Electronic
T1 Pitfall of <sup>18</sup>F-FDG PET/CT in Characterization of Relapsed Multisystem Lymphomatoid Granulomatosis
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 396
OP 397
DO 10.2967/jnmt.118.212274
VO 46
IS 4
A1 Kelly Tung
A1 Allison C. Rosenthal
A1 Fiona E. Craig
A1 Jonathan B. Ashman
A1 Ming Yang
YR 2018
UL http://tech.snmjournals.org/content/46/4/396.abstract
AB We present serial 18F-FDG PET/CT findings in a case of grade 3 pulmonary lymphomatoid granulomatosis positive for the Epstein–Barr virus. The patient experienced a transient complete response to R-CHOP chemotherapy and subsequent multisystem recurrence, predominately involving the subcutaneous region of the torso on 18F-FDG PET/CT. Biopsy of the most hypermetabolic subcutaneous lesion demonstrated grade 1 cutaneous lymphomatoid granulomatosis negative for the Epstein–Barr virus. This report highlights the role of 18F-FDG PET/CT in characterizing and monitoring disease progression and regression, as well as the limitations of 18F-FDG PET/CT in accurate grading of multisystem recurrence, given the diversity of clinical and histopathologic features of lymphomatoid granulomatosis.