Fully Automated Production of Diverse 18F-Labeled PET Tracers on the ELIXYS Multireactor Radiosynthesizer Without Hardware Modification

Mark Lazari; Jeffrey Collins; Bin Shen; Mohammed Farhoud; Daniel Yeh; Brandon Maraglia; Frederick T. Chin; David A. Nathanson; Melissa Moore; R. Michael van Dam

doi:10.2967/jnmt.114.140392

Research ArticleRADIOPHARMACY

Fully Automated Production of Diverse ¹⁸F-Labeled PET Tracers on the ELIXYS Multireactor Radiosynthesizer Without Hardware Modification

Mark Lazari, Jeffrey Collins, Bin Shen, Mohammed Farhoud, Daniel Yeh, Brandon Maraglia, Frederick T. Chin, David A. Nathanson, Melissa Moore and R. Michael van Dam

Journal of Nuclear Medicine Technology September 2014, 42 (3) 203-210; DOI: https://doi.org/10.2967/jnmt.114.140392

Mark Lazari

1Department of Bioengineering, Henry Samueli School of Engineering, UCLA, Los Angeles, California

2Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California

3Crump Institute for Molecular Imaging, David Geffen School of Medicine, UCLA, Los Angeles, California

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Jeffrey Collins

2Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California

3Crump Institute for Molecular Imaging, David Geffen School of Medicine, UCLA, Los Angeles, California

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Bin Shen

4Molecular Imaging Program at Stanford (MIPS) Department of Radiology, Stanford University, Stanford, California

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Mohammed Farhoud

5Sofie Biosciences, Inc., Culver City, California; and

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Daniel Yeh

2Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California

6Ahmanson Translational Imaging Division, David Geffen School of Medicine, UCLA, Los Angeles, California

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Brandon Maraglia

2Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California

3Crump Institute for Molecular Imaging, David Geffen School of Medicine, UCLA, Los Angeles, California

5Sofie Biosciences, Inc., Culver City, California; and

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Frederick T. Chin

4Molecular Imaging Program at Stanford (MIPS) Department of Radiology, Stanford University, Stanford, California

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David A. Nathanson

2Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California

6Ahmanson Translational Imaging Division, David Geffen School of Medicine, UCLA, Los Angeles, California

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Melissa Moore

2Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California

3Crump Institute for Molecular Imaging, David Geffen School of Medicine, UCLA, Los Angeles, California

5Sofie Biosciences, Inc., Culver City, California; and

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R. Michael van Dam

1Department of Bioengineering, Henry Samueli School of Engineering, UCLA, Los Angeles, California

2Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California

3Crump Institute for Molecular Imaging, David Geffen School of Medicine, UCLA, Los Angeles, California

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Fully Automated Production of Diverse ¹⁸F-Labeled PET Tracers on the ELIXYS Multireactor Radiosynthesizer Without Hardware Modification

Mark Lazari, Jeffrey Collins, Bin Shen, Mohammed Farhoud, Daniel Yeh, Brandon Maraglia, Frederick T. Chin, David A. Nathanson, Melissa Moore, R. Michael van Dam

Journal of Nuclear Medicine Technology Sep 2014, 42 (3) 203-210; DOI: 10.2967/jnmt.114.140392

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Fully Automated Production of Diverse ¹⁸F-Labeled PET Tracers on the ELIXYS Multireactor Radiosynthesizer Without Hardware Modification

Mark Lazari, Jeffrey Collins, Bin Shen, Mohammed Farhoud, Daniel Yeh, Brandon Maraglia, Frederick T. Chin, David A. Nathanson, Melissa Moore, R. Michael van Dam

Journal of Nuclear Medicine Technology Sep 2014, 42 (3) 203-210; DOI: 10.2967/jnmt.114.140392

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Production of diverse PET probes with limited resources: 24 18F-labeled compounds prepared with a single radiosynthesizer

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Keywords

automated radiosynthesis
radiochemistry kits
18F-FAC
18F-FEAU
18F-FMAU

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