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Journal of Nuclear Medicine Technology

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Research ArticleImaging

Evaluation of 99mTc-Succimer Dosing in Pediatric Patients

Wendy Galbraith, Anthony Nguyen, Donald L. Harrison, Xinlian Chen and Katie Talley
Journal of Nuclear Medicine Technology June 2013, 41 (2) 81-84; DOI: https://doi.org/10.2967/jnmt.112.118836
Wendy Galbraith
1University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma; and
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Anthony Nguyen
2OU Medical Center Children’s Hospital, Oklahoma City, Oklahoma
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Donald L. Harrison
1University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma; and
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Xinlian Chen
1University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma; and
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Katie Talley
2OU Medical Center Children’s Hospital, Oklahoma City, Oklahoma
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    FIGURE 1.

    Comparison of average activity per kilogram.

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    TABLE 1

    Summary of Guidelines for Dosing 99mTc-DMSA

    ParameterSNMMI (6)NACG (7)ACR (8)EANM (9,10,13)
    Activity per kilogramNA1.85 MBq/kg (0.05 mCi/kg)1.85–3.7 MBq/kg (0.05–0.1 mCi/kg)Dose card based on BW (9)
    Minimum activity∼11 MBq (0.3 mCi)18.5 MBq (0.5 mCi)11.1–37 MBq (0.3–1.0 mCi)15 MBq (0.4 mCi) (10)
    Maximum activity∼110 MBq (3.0 mCi)NA111–185 MBq (3.0–5.0 mCi)80–160 MBq (2.2–4.3 mCi) (13)
    Parallel counts or time300,000–500,000 (no time listed)NA300,000 or 5 min300,000 or ∼5 min (10)
    Pinhole counts or time∼150,000 counts or 15–20 min/imageNA100,000–150,000 counts or 10 min/image100,000–150,000 or ∼10 min/image (10)
    • NA = not applicable.

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Journal of Nuclear Medicine Technology: 41 (2)
Journal of Nuclear Medicine Technology
Vol. 41, Issue 2
June 1, 2013
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Evaluation of 99mTc-Succimer Dosing in Pediatric Patients
Wendy Galbraith, Anthony Nguyen, Donald L. Harrison, Xinlian Chen, Katie Talley
Journal of Nuclear Medicine Technology Jun 2013, 41 (2) 81-84; DOI: 10.2967/jnmt.112.118836

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Evaluation of 99mTc-Succimer Dosing in Pediatric Patients
Wendy Galbraith, Anthony Nguyen, Donald L. Harrison, Xinlian Chen, Katie Talley
Journal of Nuclear Medicine Technology Jun 2013, 41 (2) 81-84; DOI: 10.2967/jnmt.112.118836
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Keywords

  • 99mTc-dimercaptosuccinic acid
  • succimer
  • radiopharmaceutical
  • pediatric
  • administered activity
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