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Fusion of SPECT and Multidetector CT Images for Accurate Localization of Pelvic Sentinel Lymph Nodes in Prostate Cancer Patients

Hiroto Kizu, Teruhiko Takayama, Mamoru Fukuda, Masayuki Egawa, Hiroyuki Tsushima, Masato Yamada, Kenji Ichiyanagi, Kunihiko Yokoyama, Masahisa Onoguchi and Norihisa Tonami
Journal of Nuclear Medicine Technology June 2005, 33 (2) 78-82;
Hiroto Kizu
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Teruhiko Takayama
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Mamoru Fukuda
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Masayuki Egawa
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Hiroyuki Tsushima
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Masato Yamada
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Kenji Ichiyanagi
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Kunihiko Yokoyama
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Masahisa Onoguchi
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Norihisa Tonami
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  • FIGURE 1.
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    FIGURE 1.

    Landmarks (arrows) on axial slices of CT (A) and SPECT (B).

  • FIGURE 2.
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    FIGURE 2.

    Endoscopic lymphadenectomy by means of minilaparotomy.

  • FIGURE 3.
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    FIGURE 3.

    Fusion of SPECT and CT images indicating left external iliac lymph node (arrow) in case 2. (A) Coronal slice. (B) Sagittal slice. (C) Axial slice. (D) Anterior planar lymphoscintigraphic image.

  • FIGURE 4.
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    FIGURE 4.

    Fusion of SPECT and CT images indicating right obturator lymph node (arrow) in case 2. (A) Coronal slice. (B) Sagittal slice. (C) Axial slice. (D) Anterior planar lymphoscintigraphic image.

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    TABLE 1

    Surgically Excised Regional Hot Lymph Nodes in 11 Patients

    CaseSize, mm × mm (cps), of the following lymph node*:
    External iliacInternal iliacObturator
    RLRLRL
    1(252)(1,740)(110)
    26 × 4 (717)†10 × 7 (10)
    36 × 4 (34), 3 × 2 (4)
    48 × 5 (522)
    55 × 5 (196)6 × 4 (12)
    6(1,673)(105)(220)
    75 × 3 (3)‡
    89 × 6 (1)‡4 × 3 (2)‡
    99 × 4 (62)2 × 2 (27)5 × 4 (698)4 × 3 (372)
    105 × 5 (10), 7 × 5 (41)8 × 7 (179), 10 × 8 (695)4 × 4 (853)7 × 5 (684)
    1115 × 10 (430)8 × 7 (3,556)3 × 3 (349), 4 × 3 (56)2 × 2 (11)
    Total765445
    • ↵* Size measurements were not obtained for all lymph nodes. Totals represent numbers of lymph nodes.

    • ↵† Positive for lymph node metastasis.

    • ↵‡ Not detectable by lymphoscintigraphy.

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Journal of Nuclear Medicine Technology: 33 (2)
Journal of Nuclear Medicine Technology
Vol. 33, Issue 2
June 1, 2005
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Fusion of SPECT and Multidetector CT Images for Accurate Localization of Pelvic Sentinel Lymph Nodes in Prostate Cancer Patients
Hiroto Kizu, Teruhiko Takayama, Mamoru Fukuda, Masayuki Egawa, Hiroyuki Tsushima, Masato Yamada, Kenji Ichiyanagi, Kunihiko Yokoyama, Masahisa Onoguchi, Norihisa Tonami
Journal of Nuclear Medicine Technology Jun 2005, 33 (2) 78-82;

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Fusion of SPECT and Multidetector CT Images for Accurate Localization of Pelvic Sentinel Lymph Nodes in Prostate Cancer Patients
Hiroto Kizu, Teruhiko Takayama, Mamoru Fukuda, Masayuki Egawa, Hiroyuki Tsushima, Masato Yamada, Kenji Ichiyanagi, Kunihiko Yokoyama, Masahisa Onoguchi, Norihisa Tonami
Journal of Nuclear Medicine Technology Jun 2005, 33 (2) 78-82;
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  • Value of SPECT/CT for Detection and Anatomic Localization of Sentinel Lymph Nodes Before Laparoscopic Sentinel Node Lymphadenectomy in Prostate Carcinoma
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  • Localization of Metastases from Malignant Pheochromocytoma in Patients Undergoing 131I-MIBG Therapy with Manually Fused 123I-MIBG SPECT and CT Images
  • The Additional Value of SPECT/CT in Lymphatic Mapping in Breast Cancer and Melanoma
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