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Journal of Nuclear Medicine Technology

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Imaging

Off-Site Determinations of Effective Renal Plasma Flow Using Technetium-99m-MAG3 and Single Blood Sampling

Douglass Vines, Paul Denhartog, David Kwan and Masanori Ichise
Journal of Nuclear Medicine Technology March 1998, 26 (1) 23-25;
Douglass Vines
Department of Nuclear Medicine, Mount Sinai Hospital and University of Toronto, Toronto; and Mallinckrodt Medical Inc., Mississauga, Ontario, Canada
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Paul Denhartog
Department of Nuclear Medicine, Mount Sinai Hospital and University of Toronto, Toronto; and Mallinckrodt Medical Inc., Mississauga, Ontario, Canada
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David Kwan
Department of Nuclear Medicine, Mount Sinai Hospital and University of Toronto, Toronto; and Mallinckrodt Medical Inc., Mississauga, Ontario, Canada
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Masanori Ichise
Department of Nuclear Medicine, Mount Sinai Hospital and University of Toronto, Toronto; and Mallinckrodt Medical Inc., Mississauga, Ontario, Canada
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Abstract

This study evaluated the feasibility of determining effective renal plasma flow (ERPF) at an off-site central laboratory by transferring blood samples from the on-site laboratory.

Methods: Blood samples were obtained from 66 patients referred for renal imaging with 99mTc-MAG3. ERPF values were determined using the single blood sample method (BSM) at both on- and off-site laboratories. The ERPF values were classified clinically as normal or abnormal. Both the ERPF values and clinical classification were compared between on- and off-site laboratories.

Results: The off-site ERPF overestimated those on-site by 2.8% (paired Student’s t-test p < 10−5). However, off-site ERPF values highly correlated with the values obtained onsite (r = 0.99; p < 10−5). In addition, the clinical classification for each patient determined at each site was identical.

Conclusion: ERPF can be determined accurately off-site. This method should allow many nuclear medicine departments access to the ERPF determination by the BSM at a central off-site laboratory.

  • technetium-99m-MAG3
  • effective renal plasma flow
  • kidney
  • renal function
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Journal of Nuclear Medicine Technology: 26 (1)
Journal of Nuclear Medicine Technology
Vol. 26, Issue 1
March 1, 1998
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Off-Site Determinations of Effective Renal Plasma Flow Using Technetium-99m-MAG3 and Single Blood Sampling
Douglass Vines, Paul Denhartog, David Kwan, Masanori Ichise
Journal of Nuclear Medicine Technology Mar 1998, 26 (1) 23-25;

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Off-Site Determinations of Effective Renal Plasma Flow Using Technetium-99m-MAG3 and Single Blood Sampling
Douglass Vines, Paul Denhartog, David Kwan, Masanori Ichise
Journal of Nuclear Medicine Technology Mar 1998, 26 (1) 23-25;
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Keywords

  • technetium-99m-MAG3
  • effective renal plasma flow
  • kidney
  • renal function
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