PT  - JOURNAL ARTICLE
AU  - Vines, Douglass
AU  - Denhartog, Paul
AU  - Kwan, David
AU  - Ichise, Masanori
TI  - Off-Site Determinations of Effective Renal Plasma Flow Using Technetium-99m-MAG3 and Single Blood Sampling
DP  - 1998 Mar 01
TA  - Journal of Nuclear Medicine Technology
PG  - 23--25
VI  - 26
IP  - 1
4099  - http://tech.snmjournals.org/content/26/1/23.short
4100  - http://tech.snmjournals.org/content/26/1/23.full
SO  - J. Nucl. Med. Technol.1998 Mar 01; 26
AB  - This study evaluated the feasibility of determining effective renal plasma flow (ERPF) at an off-site central laboratory by transferring blood samples from the on-site laboratory. Methods: Blood samples were obtained from 66 patients referred for renal imaging with 99mTc-MAG3. ERPF values were determined using the single blood sample method (BSM) at both on- and off-site laboratories. The ERPF values were classified clinically as normal or abnormal. Both the ERPF values and clinical classification were compared between on- and off-site laboratories. Results: The off-site ERPF overestimated those on-site by 2.8% (paired Student’s t-test p < 10−5). However, off-site ERPF values highly correlated with the values obtained onsite (r = 0.99; p < 10−5). In addition, the clinical classification for each patient determined at each site was identical. Conclusion: ERPF can be determined accurately off-site. This method should allow many nuclear medicine departments access to the ERPF determination by the BSM at a central off-site laboratory.