RT Journal Article
SR Electronic
T1 Off-Site Determinations of Effective Renal Plasma Flow Using Technetium-99m-MAG3 and Single Blood Sampling
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 23
OP 25
VO 26
IS 1
A1 Vines, Douglass
A1 Denhartog, Paul
A1 Kwan, David
A1 Ichise, Masanori
YR 1998
UL http://tech.snmjournals.org/content/26/1/23.abstract
AB This study evaluated the feasibility of determining effective renal plasma flow (ERPF) at an off-site central laboratory by transferring blood samples from the on-site laboratory. Methods: Blood samples were obtained from 66 patients referred for renal imaging with 99mTc-MAG3. ERPF values were determined using the single blood sample method (BSM) at both on- and off-site laboratories. The ERPF values were classified clinically as normal or abnormal. Both the ERPF values and clinical classification were compared between on- and off-site laboratories. Results: The off-site ERPF overestimated those on-site by 2.8% (paired Student’s t-test p < 10−5). However, off-site ERPF values highly correlated with the values obtained onsite (r = 0.99; p < 10−5). In addition, the clinical classification for each patient determined at each site was identical. Conclusion: ERPF can be determined accurately off-site. This method should allow many nuclear medicine departments access to the ERPF determination by the BSM at a central off-site laboratory.