Alternative Isotope Options for Amyloidosis Imaging: A Technologist’s Perspective

Article Figures & Data

TABLE 1.

^99mTc-HMDP Cardiac Amyloidosis Protocol (1)

Protocol	Parameter	Recommendation
Prescan
Preparation	No specific preparation; no fasting required
Scan	Rest scan	Standard
Dose	370–740 MBq (10–20 mCi) ^99mTc-HMDP intravenously	Standard
Time from injection to acquisition	2 or 3 h	Standard
General imaging parameters
Field of view	Heart or chest	Standard
	Whole-body	Optional
Image type	Planar	Standard
	SPECT if planar is positive	Required
Position	Supine	Standard
	Upright	Optional
Energy window	140 keV, 15%–20%	Standard
Collimators	Low-energy, high-resolution	Standard
Matrix	Planar: 256 × 256 (minimum, 64 × 64)	Standard
	SPECT: 128 × 128 (minimum, 64 × 64)	Standard
Pixel size	3.5–6.5 mm	Standard
Planar parameters
Views	Chest: anterior and lateral	Standard
	Whole-body: from head to toe	Optional
Detector configuration	90°	Recommended
Image duration (count-based)	Planar: 750,000	Standard
	Whole-body: 20 cm/min	Optional
Magnification	1.46	Standard
SPECT parameters
Angular range	180°	Standard
	360°	Optional
Detector configuration	90°	Standard
	180°	Optional
Electrocardiographic gating	Off; nongated imaging	Standard
Number of views/detector	40/32	Standard
Time per stop	20 s/25 s	Standard
Magnification	1.46 (180° angular range) or 1.0 (360° angular range)	Recommended