Evaluation of New T₃ Uptake and Total T₄ Tests

Abstract

The T₃U and T₄ tests from Ames Co. were compared with two reference tests in their ability to classify populations of patients with regard to thyroid function. The CLINIRIA T³U is the first all-liquid T₃ uptake test that lends itself to automation. In specificity and reproducibility, it was comparable to existing methods. The CLINIRIA T₄ and the reference method were equal in misclassification of patients but were different in the range of normal values. Both tests were of equal value when compared with already established thyroid function test procedures. Any advantage over previously introduced tests may come from considerations of cost-effectiveness and ease of automation and thus depends on specific laboratory circumstances.