Steroid-Induced Activated White Adipose Tissue Detected on ¹⁸F-FDG PET/CT

Abstract

White adipose tissue (WAT) usually shows negligible ¹⁸F-FDG uptake due to negligible glucose utilization. However, corticosteroids alter the biodistribution of ¹⁸F-FDG and increase uptake in WAT. Here, we present a case of diffusely increased ¹⁸F-FDG uptake in WAT secondary to high-dose corticosteroid therapy for nephrotic syndrome.