Research ArticleTeaching Case Study

Metachronous Adenocarcinoma of the Lung in the Setting of Metastatic Gastric Neuroendocrine Tumor: Value of Elucidating Discordance on Dual-Tracer PET/CT with Ki-67 Index

Sarvesh Loharkar and Sandip Basu
Journal of Nuclear Medicine Technology March 2023, 51 (1) 75-77; DOI: https://doi.org/10.2967/jnmt.121.263415

Article Figures & Data

Figures

  • FIGURE 1.
    FIGURE 1.

    Baseline 68Ga-DOTATATE PET/CT (upper left: maximum-intensity projection image; upper right: fused coronal; lower left: transaxial CT only; and lower right: fused transaxial) showing multiple SSTR-expressing hepatic metastases (liver segment V lesion).

  • FIGURE 2.
    FIGURE 2.

    18F-FDG PET/CT after 2 cycles of peptide-receptor radionuclide therapy (upper left: maximum-intensity projection image; upper right: fused coronal; lower left: transaxial CT; and lower right: fused transaxial) showing 18F-FDG–concentrating (SUVmax, 9.6) ill-defined opacity in upper lobe of right lung.

  • FIGURE 3.
    FIGURE 3.

    Follow-up dual-tracer PET/CT maximum-intensity projections obtained 6 mo apart (right panel later than left panel) and showing disease progression in terms of increase in size and number of SSTR-expressing hepatic lesions on 68Ga-DOTATATE PET/CT and increase in size and number of 18F-FDG–avid lung lesions on 18F-FDG PET/CT.

  • FIGURE 4.
    FIGURE 4.

    Follow-up dual-tracer transaxial PET/CT images showing 18F-FDG–avid (SUVmax, 10.9), non–SSTR-expressing (SUVmax, 4.7) lung lesions in right upper lobe (A and B); non–18F-FDG-concentrating (SUVmax, 2.8), highly SSTR-expressing (SUVmax, 29.4) hypodense segment V lesion in liver and nodal mass at splenic hilum (C); and similar non–18F-FDG-concentrating (SUVmax, 2.4), highly SSTR-expressing hypodense segment VI lesion in liver (SUVmax, 26.5) (D).

Back to top

In this issue

Print
Download PDF
Article Alerts
Email Article
Citation Tools
Bookmark this article

Jump to section

Keywords