Article Figures & Data
Figures
- FIGURE 1.
No 18F-DOPA uptake in calcified benign right temporal lesion (meningioangiomatosis) (arrows). (A) From left to right: axial T2-weighted, axial T1-weighted, axial fluid-attenuated inversion recovery, and coronal T2-weighted MR images. (B) From left to right: axial 18F-DOPA PET/MR, axial 18F-DOPA PET/CT, coronal 18F-DOPA PET/CT, and axial 18F-DOPA PET images.
- FIGURE 2.
Intense 18F-DOPA uptake in recurrent diffuse intrinsic pontine glioma showing better tumor delineation of true tumor boundaries than on the MRI alone and showing that intensity of uptake is likely a prognostic parameter. (A) From left to right: coronal T2-weighted fat-saturated initial, coronal T2-weighted fat-saturated 9-mo follow-up, and coronal 18F-DOPA 9-mo follow-up PET/MR images. (B) From left to right: axial 18F-DOPA PET fused to initial MR, axial T2-weighted fat-saturated 9-mo follow-up MR, and axial 18F-DOPA 9-mo follow-up PET/MR images.
- FIGURE 3.
No clear change in size of initial diffuse intrinsic pontine glioma tumor 9 mo after initial MRI. Changes in appearance on different sequences showed T2-weighted and diffusion-weighted MRI signal distribution changes. 18F-DOPA scan fused with follow-up MRI clearly delineates tumor viability and recurrence. (A) From left to right: initial axial T1-weighted contrast-enhanced, initial axial T2-weighted, and initial axial diffusion-weighted MR images. (B) From left to right: axial 18F-DOPA T2-weighted 9-mo follow-up PET/MR, axial T2-weighted 9-mo follow-up MR, and axial diffusion-weighted 9-mo follow-up MR images. (C) From left to right: axial 18F-DOPA, coronal 18F-DOPA, and sagittal 18F-DOPA PET images.
- FIGURE 4.
A 3-y-old girl after resection of posterior fossa tumor (anaplastic ependymoma: World Health Organization grade III). Three weeks after surgery, 8-mm left-sided nodule (blue arrows) in resection cavity showed no abnormal 18F-DOPA uptake. Follow-up MRI on same day as 18F-DOPA scan showed interval reduction in size and near-complete resolution of this nodule (white arrows), most consistent with initial postoperative changes. (A) From left to right: axial T2-weighted preoperative MR, axial immediately postoperative T1-weighted contrast-enhanced MR, and axial immediately postoperative 18F-DOPA PET/MR images (B) From left to right: axial follow-up postoperative T1-weighted MR (3 wk), axial follow-up 18F-DOPA PET/MR, and axial 18F-DOPA PET images.
- FIGURE 5.
Summary diagram. EANM = European Association of Nuclear Medicine; EANO = European Association of Neuro-Oncology; RANO = Response Assessment in Neuro-Oncology; RAPNO = Response Assessment in Pediatric Neuro-Oncology; SIOPE = European Society for Paediatric Oncology; SNMMI = Society of Nuclear Medicine and Molecular Imaging.
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