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Research ArticleImaging

Comparison of Low-Energy and Medium-Energy Collimators for Thyroid Scintigraphy with 123I

Yuxin Li, Esther Choi, Artineh Hayrapetian, Emmanuel Appiah-Kubi, Jonathan Gershenson, Nazanin H. Asvadi and Gholam R. Berenji
Journal of Nuclear Medicine Technology March 2022, 50 (1) 25-29; DOI: https://doi.org/10.2967/jnmt.121.262517
Yuxin Li
1Department of Radiology, VA Greater Los Angeles Healthcare System, Los Angeles, California;
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Esther Choi
2Department of Radiology, Penn State Health, Milton S. Hershey Medical Center, Hershey, Pennsylvania;
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Artineh Hayrapetian
3UCLA Ahmanson Translational Theranostics Division, Los Angeles, California;
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Emmanuel Appiah-Kubi
4Department of Radiology, Ohio State University Wexner Medical Center, Columbus, Ohio; and
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Jonathan Gershenson
1Department of Radiology, VA Greater Los Angeles Healthcare System, Los Angeles, California;
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Nazanin H. Asvadi
5Department of Radiology, Saint Vincent Hospital, Worcester, Massachusetts
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Gholam R. Berenji
1Department of Radiology, VA Greater Los Angeles Healthcare System, Los Angeles, California;
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  • FIGURE 1.
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    FIGURE 1.

    Planar anterior view of thyroid scintigraphy from LEHR collimator and ME collimator.

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    FIGURE 2.

    Comparison of photon counts between LEHR collimator and ME collimator. (A) Total counts from whole rectangular field of view of collimator. (B–D) Counts within thyroid isocontour measured by applying 30% of threshold. A and D represent mean with SD. B and C represent median with interquartile range. *Significance was determined by Student t test. **Significance was determined by Mann–Whitney test.

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    FIGURE 3.

    Bland–Altman plot analyses of thyroid length measurement between ultrasonography with LEHR collimators (A) and ultrasonography with ME collimators (B). LOA = limit of agreement; US = ultrasonography.

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    FIGURE 4.

    Bland–Altman plot analyses of thyroid volume estimation between ultrasonography with LEHR collimators (A) and ultrasonography with ME collimators (B and C) by applying different thresholds.

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    TABLE 1.

    Siemens BiCore Collimator Specifications

    ParameterLEHRME
    Hole shapeHexagonHexagon
    Number of holes (×1,000)14814
    Hole length24.05 mm40.64 mm
    Septal thickness0.16 mm1.14 mm
    Hole diameter1.11 mm2.94 mm
    Sensitivity at 10 cm5.46 cpm/kBq (99mTc)7.43 cpm/kBq (67Ga)
    Geometric resolution at 10 cm6.4 mm (99mTc)10.8 mm (67Ga)
    System resolution at 10 cm7.5 mm (99mTc)12.5 mm (67Ga)
    Septal penetration1.5% (99mTc)1.2% (67Ga)
    Weight22.1 kg63.5 kg
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Journal of Nuclear Medicine Technology: 50 (1)
Journal of Nuclear Medicine Technology
Vol. 50, Issue 1
March 1, 2022
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Comparison of Low-Energy and Medium-Energy Collimators for Thyroid Scintigraphy with 123I
Yuxin Li, Esther Choi, Artineh Hayrapetian, Emmanuel Appiah-Kubi, Jonathan Gershenson, Nazanin H. Asvadi, Gholam R. Berenji
Journal of Nuclear Medicine Technology Mar 2022, 50 (1) 25-29; DOI: 10.2967/jnmt.121.262517

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Comparison of Low-Energy and Medium-Energy Collimators for Thyroid Scintigraphy with 123I
Yuxin Li, Esther Choi, Artineh Hayrapetian, Emmanuel Appiah-Kubi, Jonathan Gershenson, Nazanin H. Asvadi, Gholam R. Berenji
Journal of Nuclear Medicine Technology Mar 2022, 50 (1) 25-29; DOI: 10.2967/jnmt.121.262517
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Keywords

  • endocrine
  • image processing
  • collimator
  • iodine-123
  • medium energy
  • thyroid scintigraphy
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