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Research ArticleImaging

Accuracy Assessment of SUV Measurements in SPECT/CT: A Phantom Study

Fatin Halim, Hizwan Yahya, Khairul Nizam Jaafar and Syahir Mansor
Journal of Nuclear Medicine Technology September 2021, 49 (3) 250-255; DOI: https://doi.org/10.2967/jnmt.120.259168
Fatin Halim
1Oncological and Radiological Science Cluster, Advanced Medical and Dental Institute, SAINS@BERTAM, Universiti Sains Malaysia, Penang, Malaysia;
2Department of Nuclear Medicine, Penang Hospital, Penang, Malaysia; and
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Hizwan Yahya
1Oncological and Radiological Science Cluster, Advanced Medical and Dental Institute, SAINS@BERTAM, Universiti Sains Malaysia, Penang, Malaysia;
2Department of Nuclear Medicine, Penang Hospital, Penang, Malaysia; and
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Khairul Nizam Jaafar
3Nuclear Medicine Unit, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia
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Syahir Mansor
1Oncological and Radiological Science Cluster, Advanced Medical and Dental Institute, SAINS@BERTAM, Universiti Sains Malaysia, Penang, Malaysia;
3Nuclear Medicine Unit, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia
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    FIGURE 1.

    SUV images from phantom study without (A and C) and with (B and D) 4-mm gaussian postprocessing filter. Reconstructed images were achieved using 3-dimensional ordered-subset expectation maximization with 2, 10, and 20 iterations and 10 subsets (2i10s, 10i10s, and 20i10s, respectively) and with background-to-sphere ratios of 1:4 and 1:10 with high activity concentration.

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    FIGURE 2.

    Sphere-to-background ratio of 1:4 with high activity concentration. Dotted lines show true SUV for respective spheres and background.

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    FIGURE 3.

    Noise (percentage coefficient of variation [COV]) for various reconstructions for 3 largest spheres and background. i = iterations; s = subsets.

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Journal of Nuclear Medicine Technology: 49 (3)
Journal of Nuclear Medicine Technology
Vol. 49, Issue 3
September 1, 2021
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Accuracy Assessment of SUV Measurements in SPECT/CT: A Phantom Study
Fatin Halim, Hizwan Yahya, Khairul Nizam Jaafar, Syahir Mansor
Journal of Nuclear Medicine Technology Sep 2021, 49 (3) 250-255; DOI: 10.2967/jnmt.120.259168

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Accuracy Assessment of SUV Measurements in SPECT/CT: A Phantom Study
Fatin Halim, Hizwan Yahya, Khairul Nizam Jaafar, Syahir Mansor
Journal of Nuclear Medicine Technology Sep 2021, 49 (3) 250-255; DOI: 10.2967/jnmt.120.259168
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Keywords

  • quantitative
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  • phantom
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