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Research ArticleTeaching Case Studies

Axillary Lymph Nodal Metastases from Thyroid Carcinoma: Report of 2 Cases with Review of Literature

Shashank Shekhar Singh, Swathy Krishnan, Nitheeshraj K. Tigapuram, Ashwani Sood, Swayamjeet Satapathy, Manish Rohilla, Sindhu Tanigassalam and Bhagwant Rai Mittal
Journal of Nuclear Medicine Technology March 2021, 49 (1) 89-91; DOI: https://doi.org/10.2967/jnmt.120.249128
Shashank Shekhar Singh
1Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India; and
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Swathy Krishnan
1Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India; and
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Nitheeshraj K. Tigapuram
1Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India; and
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Ashwani Sood
1Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India; and
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Swayamjeet Satapathy
1Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India; and
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Manish Rohilla
2Department of Cytopathology and Gynecological Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
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Sindhu Tanigassalam
1Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India; and
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Bhagwant Rai Mittal
1Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India; and
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    FIGURE 1.

    (A) Diagnostic whole-body 131I planar anterior image showing negative findings. (B) 18F-FDG PET/CT maximum-intensity-projection image showing abnormal foci of tracer uptake in bilateral cervical, right supraclavicular, right axillary and right thoracic regions. (C–E) Fused axial PET/CT images showing right cervical lymph nodes (C, arrow), axillary lymph nodes (D, arrow), and right ALN, as well as right lung nodule (E, arrow).

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    FIGURE 2.

    Fine-needle aspiration from right ALN yielded colloid mixed material and cellular smears. (A) Tumor cells arranged in papillae and small clusters (May Grunwald–Giemsa stain; ×40). (B) Tumor papilla with rolled-up margins (May Grunwald–Giemsa stain; ×100). (C and D) Individual tumor cells showing nuclear enlargement with focal crowding and prominent intranuclear pseudo inclusion (arrows; May Grunwald–Giemsa stain; ×200).

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    FIGURE 3.

    (A–C) Posttherapy whole-body 131I planar anterior image (A) and fused axial SPECT/CT images (B and C) showing intensely tracer-avid remnant (solid black arrow), faintly tracer-avid left ALN, and highest mediastinal (red arrows) and prevascular (dashed arrow) lymph nodes. (D) Diagnostic whole-body 131I planar anterior image after 6 mo showing resolution of remnant and left ALN with faint tracer uptake in mediastinum (arrow).

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Journal of Nuclear Medicine Technology: 49 (1)
Journal of Nuclear Medicine Technology
Vol. 49, Issue 1
March 1, 2021
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Axillary Lymph Nodal Metastases from Thyroid Carcinoma: Report of 2 Cases with Review of Literature
Shashank Shekhar Singh, Swathy Krishnan, Nitheeshraj K. Tigapuram, Ashwani Sood, Swayamjeet Satapathy, Manish Rohilla, Sindhu Tanigassalam, Bhagwant Rai Mittal
Journal of Nuclear Medicine Technology Mar 2021, 49 (1) 89-91; DOI: 10.2967/jnmt.120.249128

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Axillary Lymph Nodal Metastases from Thyroid Carcinoma: Report of 2 Cases with Review of Literature
Shashank Shekhar Singh, Swathy Krishnan, Nitheeshraj K. Tigapuram, Ashwani Sood, Swayamjeet Satapathy, Manish Rohilla, Sindhu Tanigassalam, Bhagwant Rai Mittal
Journal of Nuclear Medicine Technology Mar 2021, 49 (1) 89-91; DOI: 10.2967/jnmt.120.249128
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Keywords

  • thyroid carcinoma
  • axillary lymph node
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