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Research ArticleQuality & Practice Management

Use of Advanced CT Technology to Evaluate Left Atrial Indices in Patients with a High Heart Rate or with Heart Rate Variability: The Converge Registry

Lavanya Cherukuri, Divya Birudaraju, April Kinninger, Bhanu T. Chaganti, Sivakrishna Pidikiti, Ryan G. Pozon, Anne Concepcion G. Pozon, Suvasini Lakshmanan, Suraj Dahal, Sajad Hamal, Ferdinand Flores, Dialing Christopher, Daniele Andreini, Gianluca Pontone, Edoardo Conte, Rine Nakanishi, Rachael O’Rourke, Christian Hamilton-Craig, Khurram Nasir, Sion K. Roy, Song Shou Mao and Matthew J. Budoff
Journal of Nuclear Medicine Technology March 2021, 49 (1) 65-69; DOI: https://doi.org/10.2967/jnmt.120.253781
Lavanya Cherukuri
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Divya Birudaraju
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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April Kinninger
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Bhanu T. Chaganti
2Texas Tech University Health Sciences Center, El Paso, Texas
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Sivakrishna Pidikiti
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Ryan G. Pozon
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Anne Concepcion G. Pozon
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Suvasini Lakshmanan
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Suraj Dahal
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Sajad Hamal
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Ferdinand Flores
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Dialing Christopher
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Daniele Andreini
3Centro Cardiologico Monzino, IRCCS, Milan, Italy
4Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, Milan, Italy
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Gianluca Pontone
3Centro Cardiologico Monzino, IRCCS, Milan, Italy
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Edoardo Conte
3Centro Cardiologico Monzino, IRCCS, Milan, Italy
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Rine Nakanishi
5Department of Cardiovascular Medicine, Toho University Graduate School of Medicine, Tokyo, Japan
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Rachael O’Rourke
6Department of Medical Imaging, Prince Charles Hospital, Brisbane, Queensland, Australia; and
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Christian Hamilton-Craig
6Department of Medical Imaging, Prince Charles Hospital, Brisbane, Queensland, Australia; and
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Khurram Nasir
7Baptist Heart Medical Group, Miami, Florida
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Sion K. Roy
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Song Shou Mao
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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Matthew J. Budoff
1Lundquist Institute for Biomedical Innovation, Harbor UCLA Medical Center, Torrance, California
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    TABLE 1

    Baseline Characteristics

    CharacteristicTotal (n = 223)HiHR (n = 121)AFib (n = 102)P
    Age (y)61.7 ± 11.962.7 ± 12.560.5 ± 11.00.16
    Men146 (65)74 (61)72 (71)0.14
    Chest pain42 (19)29 (24)13 (13)0.03
    Hypertension157 (70)72 (60)85 (83)0.0001
    Dyslipidemia140 (63)81 (67)59 (58)0.16
    Diabetes mellitus67 (30)24 (20)43 (42)0.0003
    History of myocardial infarction31 (14)10 (8)21 (21)0.008
    Current smoking19 (9)7 (6)12 (12)0.11
    Body mass index (kg/m2)30.6 ± 6.728.7 ± 5.932.8 ± 6.9<0.0001
    Body surface area (m2)2.0 ± 0.32.0 ± 0.32.1 ± 0.30.03
    Heart rate (bpm)71.4 ± 9.871.4 ± 9.866.5 ± 10.10.01
    Systolic blood pressure (mm Hg)131.3 + 19.2136.1 ± 18.6125.5 ± 18.4<0.0001
    Diastolic blood pressure (mm Hg)78.8 ± 10.978.2 ± 11.179.5 ± 10.80.3893
    Coronary artery calcium score631.65 ± 1,294.9724.6 ± 1,416.8524.1 ± 1,135.40.227
    LAV (mL)123.4 ± 52.4102.1 ± 36.5148.6 ± 57.2<0.0001
    LAVI (mL/m2)61.1 ± 25.751.5 ± 19.072.4 ± 28.1<0.0001
    • All comparisons between HiHR and AFib groups were performed using Student t test, Wilcoxon rank-sum test, or χ2 test. Qualitative data are number followed by percentage in parentheses; continuous data are mean ± SD.

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    TABLE 2

    Relationship Between Left Atrial Measurements and HiHR or AFib Subjects

    ParameterUnivariate, unadjustedMultivariate, adjusted*
    βSEPβSEP
    LAV−46.426.33<0.0001−41.186.76<0.0001
    LAVI−20.863.17<0.0001−23.103.39<0.0001
    • ↵* Adjusted for age, body mass index, sex, diabetic status, hypertension, hyperlipidemia, history of myocardial infarction and smoking habits.

    • β = standardized regression coefficient.

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Journal of Nuclear Medicine Technology: 49 (1)
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Use of Advanced CT Technology to Evaluate Left Atrial Indices in Patients with a High Heart Rate or with Heart Rate Variability: The Converge Registry
Lavanya Cherukuri, Divya Birudaraju, April Kinninger, Bhanu T. Chaganti, Sivakrishna Pidikiti, Ryan G. Pozon, Anne Concepcion G. Pozon, Suvasini Lakshmanan, Suraj Dahal, Sajad Hamal, Ferdinand Flores, Dialing Christopher, Daniele Andreini, Gianluca Pontone, Edoardo Conte, Rine Nakanishi, Rachael O’Rourke, Christian Hamilton-Craig, Khurram Nasir, Sion K. Roy, Song Shou Mao, Matthew J. Budoff
Journal of Nuclear Medicine Technology Mar 2021, 49 (1) 65-69; DOI: 10.2967/jnmt.120.253781

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Use of Advanced CT Technology to Evaluate Left Atrial Indices in Patients with a High Heart Rate or with Heart Rate Variability: The Converge Registry
Lavanya Cherukuri, Divya Birudaraju, April Kinninger, Bhanu T. Chaganti, Sivakrishna Pidikiti, Ryan G. Pozon, Anne Concepcion G. Pozon, Suvasini Lakshmanan, Suraj Dahal, Sajad Hamal, Ferdinand Flores, Dialing Christopher, Daniele Andreini, Gianluca Pontone, Edoardo Conte, Rine Nakanishi, Rachael O’Rourke, Christian Hamilton-Craig, Khurram Nasir, Sion K. Roy, Song Shou Mao, Matthew J. Budoff
Journal of Nuclear Medicine Technology Mar 2021, 49 (1) 65-69; DOI: 10.2967/jnmt.120.253781
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