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Research ArticleImaging

Using Abnormal Respiratory Motion on Myocardial Perfusion Scintigraphy as an Opportunity to Screen for Obstructive Sleep Apnea

Justin G. Peacock, Ilsup Yoon, Kevin P. Banks and Stephen A. Rosenblatt
Journal of Nuclear Medicine Technology December 2020, 48 (4) 336-339; DOI: https://doi.org/10.2967/jnmt.120.248054
Justin G. Peacock
1Department of Radiology, San Antonio Military Medical Center, San Antonio, Texas; and
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Ilsup Yoon
1Department of Radiology, San Antonio Military Medical Center, San Antonio, Texas; and
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Kevin P. Banks
1Department of Radiology, San Antonio Military Medical Center, San Antonio, Texas; and
2Department of Radiology, Uniformed Services University of the Health Sciences, Bethesda, Maryland
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Stephen A. Rosenblatt
1Department of Radiology, San Antonio Military Medical Center, San Antonio, Texas; and
CNMT, ARRT
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    FIGURE 1.

    Representative images from stress supine, stress upright, and rest upright MPS panograms demonstrating abnormal ASRM results on left and normal results on right.

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    TABLE 1

    Patient Characteristics for Total Study Population

    Characteristicn%
    Total patients154
    ASRM5435.1
    Hypertension9561.7
    Body mass index > 35 kg/m22113.6
    Age > 5014493.5
    Sex (M)8756.5
    ≥3 OSA risk factors6542.2
    OSA diagnosis2616.9
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    TABLE 2

    Comparison of Characteristics for Patients with Normal Respiratory Motion and ASRM During MPS

    CharacteristicASRMNormalP*
    Total patients54100
    Hypertension32 (59.3%)63 (63.0%)0.65
    Body mass index > 357 (13.0%)14 (14.0%)0.86
    Age > 5048 (88.9%)96 (96.0%)0.09
    Sex (M)36 (66.7%)51 (51.0%)0.06
    ≥3 OSA risk factors24 (44.4%)41 (41.0%)0.68
    OSA diagnosis9 (16.7%)17 (17.0%)0.96
    • ↵* z test for comparison of 2 population proportions at α < 0.05 level.

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    TABLE 3

    Comparison of Characteristics for Patients with ASRM or High (3 or More) OSA Risk Factors

    CharacteristicASRM≥3 OSA RFsP*
    Total patients5465
    Hypertension32 (59.3%)62 (95.4%)<0.00001
    Body mass index > 357 (13.0%)18 (27.7%)0.05
    Age > 5048 (88.9%)64 (98.5%)0.03
    Sex (M)36 (66.7%)56 (86.2%)0.01
    OSA diagnosis9 (16.7%)14 (21.5%)0.51
    • * z test for comparison of 2 population proportions at α < 0.05 level.

    • View popup
    TABLE 4

    Statistics Comparing Standard Test (High OSA Risk Factors) with Proposed Test (ASRM)

    Category%95% confidence interval
    Sensitivity36.925.3–49.8
    Specificity66.355.5–76.0
    Positive predictive value44.434.2–55.2
    Negative predictive value59.053.2–64.6
    Accuracy53.945.7–62.0
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Journal of Nuclear Medicine Technology: 48 (4)
Journal of Nuclear Medicine Technology
Vol. 48, Issue 4
December 1, 2020
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Using Abnormal Respiratory Motion on Myocardial Perfusion Scintigraphy as an Opportunity to Screen for Obstructive Sleep Apnea
Justin G. Peacock, Ilsup Yoon, Kevin P. Banks, Stephen A. Rosenblatt
Journal of Nuclear Medicine Technology Dec 2020, 48 (4) 336-339; DOI: 10.2967/jnmt.120.248054

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Using Abnormal Respiratory Motion on Myocardial Perfusion Scintigraphy as an Opportunity to Screen for Obstructive Sleep Apnea
Justin G. Peacock, Ilsup Yoon, Kevin P. Banks, Stephen A. Rosenblatt
Journal of Nuclear Medicine Technology Dec 2020, 48 (4) 336-339; DOI: 10.2967/jnmt.120.248054
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Keywords

  • myocardial perfusion study
  • obstructive sleep apnea
  • D-SPECT
  • respiratory motion
  • sleep apnea risk factors
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