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Journal of Nuclear Medicine Technology

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Review ArticleTeaching Case Studies

Glucocorticoid-Induced Hypermetabolism in White Adipose Tissue in Cushing Syndrome

Sasha O. Staack, Allison C. Rosenthal, Curtiss B. Cook and Ming Yang
Journal of Nuclear Medicine Technology September 2020, 48 (3) 285-286; DOI: https://doi.org/10.2967/jnmt.119.237545
Sasha O. Staack
1Department of Radiology, Mayo Clinic, Scottsdale, Arizona
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Allison C. Rosenthal
2Department of Hematology/Oncology, Mayo Clinic, Scottsdale, Arizona; and
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Curtiss B. Cook
3Division of Endocrinology, Mayo Clinic, Scottsdale, Arizona
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Ming Yang
1Department of Radiology, Mayo Clinic, Scottsdale, Arizona
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    FIGURE 1.

    Maximum-intensity projections of baseline (A) and follow-up (B) 18F-FDG PET/CT scans demonstrate resolution of numerous cutaneous and right-temporal-lobe tracer-avid lesions (arrow in B indicates 18F-FDG injection site).

  • FIGURE 2.
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    FIGURE 2.

    Sagittal fused images at baseline (A) and follow-up (B) show thickened subcutaneous white adipose tissue with increased 18F-FDG uptake at face, neck, and back. Axial fused images of thighs at baseline (C) and follow-up (D) reveal bilateral muscle wasting and hypermetabolic intermuscular adipose tissue.

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Journal of Nuclear Medicine Technology: 48 (3)
Journal of Nuclear Medicine Technology
Vol. 48, Issue 3
September 1, 2020
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Glucocorticoid-Induced Hypermetabolism in White Adipose Tissue in Cushing Syndrome
Sasha O. Staack, Allison C. Rosenthal, Curtiss B. Cook, Ming Yang
Journal of Nuclear Medicine Technology Sep 2020, 48 (3) 285-286; DOI: 10.2967/jnmt.119.237545

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Glucocorticoid-Induced Hypermetabolism in White Adipose Tissue in Cushing Syndrome
Sasha O. Staack, Allison C. Rosenthal, Curtiss B. Cook, Ming Yang
Journal of Nuclear Medicine Technology Sep 2020, 48 (3) 285-286; DOI: 10.2967/jnmt.119.237545
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Keywords

  • Cushing syndrome
  • White fat
  • Glucocorticoids
  • PET/CT
  • FDG
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