Article Figures & Data
Figures
- FIGURE 1.
Groups of bladder activity (encircles or arrowed). SUVmax threshold in all images is 7.0.
- FIGURE 2.
Bladder radioactivity and volume scatterplot. Spearman ρ = −0.64 (P < 0.001).
- FIGURE 3.
(Top) Bladder SUVmax and SUVmean difference between protocols. (Bottom) Distribution of different bladder activity groups between protocols. *Statistically significant difference (P < 0.05). Mdn = median.
Tables
Parameter Data Age (y) 69 (64–73) 18F-fluciclovine dose (MBq) 381.1 (362.6–392.2) Aorta SUVmean 1.6 (1.4–1.8) Marrow SUVmean 3.3 (2.7–3.9) Liver SUVmean 8.6 (7.5–10.3) Bladder SUVmax 3.1 (1.1–6.0) Bladder SUVmean 1.6 (1.6–3.6) Bladder SUVmean/aorta SUVmean ratio 1.1 (0.4–2.3) Bladder SUVmean/marrow SUVmean ratio 0.5 (0.2–1.1) Bladder SUVmean/liver SUVmean ratio 0.2 (0.1–0.5) Bladder radioactivity Bladder visualized on maximum-intensity projection 53.5% (85/159) Quantitation Insignificant (bladder SUVmean < aorta SUVmean) 48.4% (77/159) Mild (bladder SUVmean ≥ aorta SUVmean < marrow SUVmean) 20.8% (33/159) Moderate (bladder SUVmean ≥ marrow SUVmean < liver SUVmean) 22.0% (35/159) Intense (bladder SUVmean ≥ liver SUVmean) 8.8% (14/159) Bladder volume (mL) Bladder volume (n = 159) 34.4 (18.6–77.9) Insignificant (n = 77) 64.9 (43.7–102.4), P < 0.001 Mild (n = 33) 26.4 (16.9–62.5), P = 0.004 Moderate (n = 35) 20.7 (14.2–30.9), P < 0.001 Intense (n = 14) 20.2 (14.1–26.3), P < 0.001 Data are median or percentage, with IQR or n in parentheses. Total n = 159.
- TABLE 2
Quantification Differences and 18F-Fluciclovine Bladder Activity Comparison Between 2 Different Protocol Groups
Parameter Voiding protocol (n = 36) Nonvoiding protocol (n = 123) P Age (y) 67 (67, 63) 69 (64, 74) 0.21 18F-fluciclovine dose (MBq) 381.1 (362.6, 399.6) 381.1 (362.6, 392.2) 0.49 Aorta SUVmean 1.5 (1.3,1.6) 1.6 (1.4, 1.8) 0.003 Marrow SUVmean 3.2 (2.7,3.8) 3.4 (2.7, 4.0) 0.12 Liver SUVmean 8.4 (7.5, 9.5) 8.7 (7.5, 10.3) 0.31 Bladder SUVmax 4.9 (3.4, 8.1) 2.1 (1.1, 5.6) 0.001 Bladder SUVmean 2.8 (2.1, 6.0) 1.3 (0.5, 2.8) <0.001 Bladder SUVmean/aorta SUVmean ratio 2.2 (1.5, 4.4) 0.8 (0.4, 1.8) <0.001 Bladder SUVmean/marrow SUVmean ratio 1.1 (0.6, 2.2) 0.4 (0.2, 0.9) <0.001 Bladder SUVmean/liver SUVmean ratio 0.4 (0.2, 0.7) 0.2 (0.1, 0.3) <0.001 Volume (mL) 18.0 (12.6, 30.6) 51.9 (25.4, 87.1) <0.001 Bladder radioactivity (%) Bladder visualized on maximum-intensity projection 77.8% (28/36) 46.3% (57/123) <0.001 Quantitation Insignificant (bladder SUVmean < aorta SUVmean) 19.4% (7/36) 56.9% (70/123) <0.001 Mild (bladder SUVmean ≥ aorta SUVmean < marrow SUVmean) 19.4% (7/36) 21.1% (26/123) 0.826 Moderate (bladder SUVmean ≥ marrow SUVmean < liver SUVmean) 38.9% (14/36) 17.1% (21/123) 0.005 Intense (bladder SUVmean ≥ liver SUVmean) 22.2% (8/36) 4.9% (6/123) <0.001 Bladder volume (mL) Insignificant 36.5 (16.5, 66.0) 71.2 (49.2, 104.8) 0.039 Mild 15.4 (8.0, 18.1) 31.1 (21.0, 73.9) 0.015 Moderate 19.0 (12.60, 30.11) 20.9 (15.5, 30.9) 0.381 Intense 18.2 (12.6, 22.4) 24.4 (17.7, 27.2) 0.196 Data are median or percentage, with IQR or n in parentheses.
