Assessing the Effect of Various Blood Glucose Levels on 18F-FDG Activity in the Brain, Liver, and Blood Pool

Ismet Sarikaya; Ali Sarikaya; Prem Sharma

doi:10.2967/jnmt.119.226969

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Assessing the Effect of Various Blood Glucose Levels on ¹⁸F-FDG Activity in the Brain, Liver, and Blood Pool

Ismet Sarikaya, Ali Sarikaya and Prem Sharma

Journal of Nuclear Medicine Technology December 2019, 47 (4) 313-318; DOI: https://doi.org/10.2967/jnmt.119.226969

Ismet Sarikaya

1Department of Nuclear Medicine, Kuwait University Faculty of Medicine, Safat, Kuwait

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Ali Sarikaya

2Department of Nuclear Medicine, Trakya University Faculty of Medicine, Edirne, Turkey; and

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Prem Sharma

3Dasman Diabetes Institute, Biostatistics Unit, Al Kuwayt, Kuwait

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FIGURE 1.
SUV and blood glucose curves for brain (SUV_max), blood pool (SUV_mean), and liver (SUV_mean).
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FIGURE 2.
Glucose-corrected brain SUV_max as compared with measured normal brain SUV_max at blood glucose of 81–110 mg/dL.

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TABLE 1
Reduction in Brain ¹⁸F-FDG Uptake as Compared with Normal Values
Blood glucose (mg/dL) Approximate reduction (%) Reduction factor (f)
111–120 20 1.25
121–140 35 1.5
141–160 50 2.0
161–200 60 2.5
≥201 65 2.8

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Journal of Nuclear Medicine Technology

Vol. 47, Issue 4

December 1, 2019

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Assessing the Effect of Various Blood Glucose Levels on ¹⁸F-FDG Activity in the Brain, Liver, and Blood Pool

Ismet Sarikaya, Ali Sarikaya, Prem Sharma

Journal of Nuclear Medicine Technology Dec 2019, 47 (4) 313-318; DOI: 10.2967/jnmt.119.226969

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Assessing the Effect of Various Blood Glucose Levels on ¹⁸F-FDG Activity in the Brain, Liver, and Blood Pool

Ismet Sarikaya, Ali Sarikaya, Prem Sharma

Journal of Nuclear Medicine Technology Dec 2019, 47 (4) 313-318; DOI: 10.2967/jnmt.119.226969

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Blood glucose
18F-FDG
brain
liver
blood pool

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Assessing the Effect of Various Blood Glucose Levels on ¹⁸F-FDG Activity in the Brain, Liver, and Blood Pool

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Blood glucose (mg/dL)	Approximate reduction (%)	Reduction factor (f)
111–120	20	1.25
121–140	35	1.5
141–160	50	2.0
161–200	60	2.5
≥201	65	2.8