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Review ArticleTeaching Case Studies

Bilateral Orbital Soft-Tissue Metastases from Renal Neuroendocrine Tumor: Successful Theranostic Application of 68Ga/177Lu-DOTATATE with Improvement of Vision

Rahul V. Parghane and Sandip Basu
Journal of Nuclear Medicine Technology June 2019, 47 (2) 171-172; DOI: https://doi.org/10.2967/jnmt.118.217455
Rahul V. Parghane
Radiation Medicine Centre, Tata Memorial Hospital Annexe, Mumbai, India; and Homi Bhabha National Institute, Mumbai, India
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Sandip Basu
Radiation Medicine Centre, Tata Memorial Hospital Annexe, Mumbai, India; and Homi Bhabha National Institute, Mumbai, India
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    FIGURE 1.

    (A) 68Ga-DOTATATE PET/CT showing increased tracer uptake in widespread metastatic skeletal lesions; in cervical, mediastinal, abdominopelvic lymph nodes; and bilaterally in orbital soft-tissue lesions. (B) MRI of head showing oval to rounded T2-hyperintense and T1-hypointense lesions with moderate homogeneous enhancement involving left lateral rectus, left inferior oblique, right lateral rectus, and right inferior oblique muscles in intraconal locations with compression of left optic nerve, along with abnormal tracer uptake on fused PET/MRI. (C) Scan at 24 h after PRRT demonstrating adequate tracer uptake in multiple metastatic lesions.

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Journal of Nuclear Medicine Technology: 47 (2)
Journal of Nuclear Medicine Technology
Vol. 47, Issue 2
June 1, 2019
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Bilateral Orbital Soft-Tissue Metastases from Renal Neuroendocrine Tumor: Successful Theranostic Application of 68Ga/177Lu-DOTATATE with Improvement of Vision
Rahul V. Parghane, Sandip Basu
Journal of Nuclear Medicine Technology Jun 2019, 47 (2) 171-172; DOI: 10.2967/jnmt.118.217455

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Bilateral Orbital Soft-Tissue Metastases from Renal Neuroendocrine Tumor: Successful Theranostic Application of 68Ga/177Lu-DOTATATE with Improvement of Vision
Rahul V. Parghane, Sandip Basu
Journal of Nuclear Medicine Technology Jun 2019, 47 (2) 171-172; DOI: 10.2967/jnmt.118.217455
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Keywords

  • Renal Neuroendocrine Tumor
  • orbital metastases
  • 68Ga-DOTATATE
  • 177Lu-DOTATATE
  • PRRT
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