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Research ArticleImaging

Comparison of the Variability of SUV Normalized by Skeletal Volume with the Variability of SUV Normalized by Body Weight in 18F-Fluoride PET/CT

José Flávio Gomes Marin, Paulo Schiavom Duarte, José Willegaignon de Amorim de Carvalho, Heitor Naoki Sado, Marcelo Tatit Sapienza and Carlos Alberto Buchpiguel
Journal of Nuclear Medicine Technology March 2019, 47 (1) 60-63; DOI: https://doi.org/10.2967/jnmt.118.215111
José Flávio Gomes Marin
1Division of Nuclear Medicine, São Paulo Cancer Institute, São Paulo, Brazil; and
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Paulo Schiavom Duarte
1Division of Nuclear Medicine, São Paulo Cancer Institute, São Paulo, Brazil; and
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José Willegaignon de Amorim de Carvalho
1Division of Nuclear Medicine, São Paulo Cancer Institute, São Paulo, Brazil; and
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Heitor Naoki Sado
1Division of Nuclear Medicine, São Paulo Cancer Institute, São Paulo, Brazil; and
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Marcelo Tatit Sapienza
2University of São Paulo Medical School, São Paulo, Brazil
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Carlos Alberto Buchpiguel
1Division of Nuclear Medicine, São Paulo Cancer Institute, São Paulo, Brazil; and
2University of São Paulo Medical School, São Paulo, Brazil
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  • FIGURE 1.
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    FIGURE 1.

    Coronal (A) and sagittal (B) 3-dimensional volume-rendered projections of wsVOI and corresponding coronal (C) and sagittal (D) maximum-intensity projections of near-normal 18F-NaF PET study (BW SUVmean, 2.65; SV SUVmean, 0.25; WN SUVmean, 0.05; SV, 5.3 L).

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    TABLE 1

    Characteristics of Patients

    CharacteristicData
    Sex (n)
     Female131 (80.37%)
     Male32 (19.63%)
    Age (y)
     Mean ± SD52.66 ± 13.18
     Range91.09–24.05
    Creatinine (mg/dL)
     Mean ± SD0.75 ± 0.19
     Range1.53–0.28
    Weight (kg)
     Mean ± SD67.07 ± 12.31
     Range108.00–39.00
    SV (L)
     Mean ± SD5.72 ± 0.86
     Range8.76–3.57
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    TABLE 2

    Whole-Skeleton SUVmean Normalized by BW, SV, and WN for 163 Studies Analyzed

    Whole-skeleton SUVmean parameterMeanSDMaximumMinimum
    BW SUVmean2.600.524.221.5
    SV SUVmean0.220.040.330.12
    WN SUVmean0.040.010.070.02
    BW SUVmean variability0.160.120.620.00
    SV SUVmean variability0.130.100.470.00
    WN SUVmean variability0.160.120.670.00
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Journal of Nuclear Medicine Technology: 47 (1)
Journal of Nuclear Medicine Technology
Vol. 47, Issue 1
March 1, 2019
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Comparison of the Variability of SUV Normalized by Skeletal Volume with the Variability of SUV Normalized by Body Weight in 18F-Fluoride PET/CT
José Flávio Gomes Marin, Paulo Schiavom Duarte, José Willegaignon de Amorim de Carvalho, Heitor Naoki Sado, Marcelo Tatit Sapienza, Carlos Alberto Buchpiguel
Journal of Nuclear Medicine Technology Mar 2019, 47 (1) 60-63; DOI: 10.2967/jnmt.118.215111

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Comparison of the Variability of SUV Normalized by Skeletal Volume with the Variability of SUV Normalized by Body Weight in 18F-Fluoride PET/CT
José Flávio Gomes Marin, Paulo Schiavom Duarte, José Willegaignon de Amorim de Carvalho, Heitor Naoki Sado, Marcelo Tatit Sapienza, Carlos Alberto Buchpiguel
Journal of Nuclear Medicine Technology Mar 2019, 47 (1) 60-63; DOI: 10.2967/jnmt.118.215111
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Keywords

  • 18F-NaF
  • 18F-fluoride
  • PET/CT
  • SUV
  • normalization
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