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Review ArticleTeaching Case Studies

18F-FDG PET/CT for the Evaluation of Primary Eosinophilic Granuloma of the Hypothalamus

Anna Eshghi, Robert Klein, Naghmehossadat Eshghi and Phillip H. Kuo
Journal of Nuclear Medicine Technology September 2018, 46 (3) 290-291; DOI: https://doi.org/10.2967/jnmt.118.209957
Anna Eshghi
1Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona
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Robert Klein
2Department of Pathology, Banner University Medical Center, Tucson, Arizona
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Naghmehossadat Eshghi
3Department of Medical Imaging, University of Arizona, Tucson, Arizona; and
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Phillip H. Kuo
3Department of Medical Imaging, University of Arizona, Tucson, Arizona; and
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    FIGURE 1.

    (A–C) Transaxial T1-weighted unenhanced MR (A), T1-weighted gadolinium-enhanced MR (B), and unenhanced CT (C) images show hypothalamic lesion (encircled in yellow) to be strongly enhanced and isodense to gray matter. (D–F) Axial (D), sagittal (E), and coronal (F) 18F-FDG PET images reveal intense uptake in hypothalamic mass.

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    FIGURE 2.

    Histopathologic photomicrograph (hematoxylin and eosin, ×400) shows numerous eosinophils and histiocytes (arrows).

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    FIGURE 3.

    18F-FDG PET anterior whole-body maximum-intensity projection shows intensely 18F-FDG–avid hypothalamic lesion (arrow) and no other sites of disease.

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Journal of Nuclear Medicine Technology: 46 (3)
Journal of Nuclear Medicine Technology
Vol. 46, Issue 3
September 1, 2018
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18F-FDG PET/CT for the Evaluation of Primary Eosinophilic Granuloma of the Hypothalamus
Anna Eshghi, Robert Klein, Naghmehossadat Eshghi, Phillip H. Kuo
Journal of Nuclear Medicine Technology Sep 2018, 46 (3) 290-291; DOI: 10.2967/jnmt.118.209957

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18F-FDG PET/CT for the Evaluation of Primary Eosinophilic Granuloma of the Hypothalamus
Anna Eshghi, Robert Klein, Naghmehossadat Eshghi, Phillip H. Kuo
Journal of Nuclear Medicine Technology Sep 2018, 46 (3) 290-291; DOI: 10.2967/jnmt.118.209957
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Keywords

  • molecular imaging
  • oncology
  • 18F-FDG PET/CT
  • Eosinophilic Granuloma
  • Langerhans cell histiocytosis
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