Article Figures & Data
Figures
- FIGURE 1.
Scatterplots of mGFR vs. eGFR values for MDRD and CKD-EPI (SCr), CKD-EPI (CysC), and CKD-EPI (CysC+SCr). Graphs in left-hand column use UV/P 99mTc-DTPA method for mGFR as reference. Corresponding graphs in right-hand column use plasma 99mTc-DTPA method. Line of identity (dashed line), linear line fit (solid line), and 95% confidence intervals (thin dotted lines) are shown for each set of comparisons.
- FIGURE 2.
Scatterplots of mGFR vs. eGFR values for CKD-EPI (CysC) and CKD-EPI (CysC+SCr). Graphs in left-hand column use UV/P 99mTc-DTPA method for mGFR as reference. Corresponding graphs in right-hand column use plasma 99mTc-DTPA method. Line of identity (dashed line), linear line fit (solid line), and 95% confidence intervals (thin dotted lines) are shown for each set of comparisons.
Tables
- TABLE 1
Descriptive Statistics for 2 99mTc-DTPA Methods for mGFR and 4 Equations for eGFR in 54 Patients with Hepatic Cirrhosis
GFR method Mean (mL/min) SD Range Plasma DTPA mGFR 96.40 31.89 52.45–189.78 UV/P DTPA mGFR 88.63 43.33 34.95–262.60 MDRD 94.86 23.95 47.42–169.56 CKD-EPI (SCr) 99.09 20.86 51.35–138.38 CKD-EPI (CysC) 95.24 27.49 42.97–165.04 CKD-EPI (CysC+SCr) 97.25 22.82 45.96–154.79 - TABLE 2
Comparison of Performance of Equations for eGFR to 2 99mTc-DTPA Reference Methods for mGFR in Patients with Hepatic Cirrhosis
Reference GFR method Estimating equation Parameter UV/P DTPA mGFR Plasma DTPA mGFR MDRD Accuracy p10 29.63% 35.19% Accuracy p20 48.15% 68.52% Accuracy p30 57.41% 88.89% Precision 16.45 17.50 Mean bias −6.23 (−14.70 to 2.23) 1.54 (−4.73 to 7.86) Mean percentage bias 19.32% 2.53% Correlation 0.72 (0.56–0.83) 0.69 (0.52–0.81) CKD-EPI (SCr) Accuracy p10 20.37% 35.19% Accuracy p20 38.89% 64.81% Accuracy p30 55.56% 83.33% Precision 17.28 15.06 Mean bias −10.46 (−20.22 to −0.70) −2.69 (−8.93 to 3.55) Mean percentage bias 26.03% 17.90% Correlation 0.57 (0.36–0.73) 0.70 (0.53–0.81) CKD-EPI (CysC) Accuracy p10 22.22% 31.48% Accuracy p20 44.44% 61.11% Accuracy p30 59.26% 77.78% Precision 25.55 19.59 Mean bias −6.61 (−16.73 to 3.50) 1.16 (−5.13 to 7.44) Mean percentage bias 34.84% 19.51% Correlation 0.53 (0.30–0.70) 0.71 (0.54–0.82) CKD-EPI (CysC+SCr) Accuracy p10 16.67% 42.59% Accuracy p20 50.00% 75.93% Accuracy p30 61.11% 85.19% Precision 18.13 14.18 Mean bias −8.63 (−17.99 to 0.74) −0.85 (−6.25 to 4.54) Mean percentage bias 23.21% 15.04% Correlation 0.62 (0.42–0.76) 0.79 (0.66–0.87) Data in parentheses are 95% confidence intervals.
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