Article Figures & Data
Figures
- FIGURE 1.
Manual registration of PET and CT-attenuation images. PET image was moved over CT image in transaxial (A), coronal (B), and sagittal (C) views with special attention to preventing LV myocardial uptake in PET from overlapping lung parenchyma in CT. A color version of this figure is available as a supplemental file at http://tech.snmjournals.org.
- FIGURE 2.
Eight sets of cardiac PET/CT images, including reference without misregistration (A) and 7 different degrees of artificial misregistration between PET and CT images in both x- and z-directions (1-mm [B], 2-mm [C], 3-mm [D], 4-mm [E], 5-mm [F], 10-mm [G], and 15-mm [H]). Top and bottom sets of images are transaxial and coronal, respectively. A color version of this figure is available as a supplemental file at http://tech.snmjournals.org.
- FIGURE 3.
Myocardial 13N-ammonia PET images demonstrating effects of no misregistration (A) and of 1-mm (B), 2-mm (C), 3-mm (D), 4-mm (E), 5-mm (F), 10-mm (G), and 15-mm (H) misregistration in both x- and z-directions in representative case (61-y-old man). When greater than 10 mm, misregistration had noticeable effect on inhomogeneity of LV short-axis PET/CT images. Artifactual reduction in uptake is prominent in anterior and lateral walls of heart. A color version of this figure is available as a supplemental file at http://tech.snmjournals.org.
- FIGURE 4.
Uptake ratios of anterior, inferior, and lateral walls with respect to septum (A/S, I/S, L/S, respectively) as function of misregistration degree. Error bars indicate SD.
Tables
Degree of misregistration Site 0 mm 1 mm 2 mm 3 mm 4 mm 5 mm 10 mm 15 mm Anterior wall Subject 1 0 0 0 0 0 1 2 3 Subject 2 0 0 0 0 1 1 3 3 Subject 3 0 0 0 1 1 1 2 3 Subject 4 0 0 0 0 0 0 1 3 Subject 5 1 1 1 1 1 1 2 3 Subject 6 0 0 0 0 0 1 2 3 Subject 7 1 1 1 1 1 2 3 3 Subject 8 0 0 0 0 0 0 2 3 P (vs. reference) — 1.00 1.00 0.99 0.89 0.23 <0.01 <0.01 Inferior wall Subject 1 1 1 1 1 1 1 1 2 Subject 2 0 0 0 0 0 1 1 1 Subject 3 0 0 0 1 1 1 2 2 Subject 4 2 2 2 2 2 2 2 2 Subject 5 2 2 2 2 2 2 2 2 Subject 6 1 1 1 1 1 1 1 2 Subject 7 3 3 3 3 3 3 3 3 Subject 8 1 1 1 1 1 1 2 2 P (vs. reference) — 1.00 1.00 1.00 1.00 0.99 0.82 0.40 Lateral wall Subject 1 0 0 0 0 0 0 2 3 Subject 2 0 0 0 0 1 1 2 3 Subject 3 0 0 0 1 1 1 2 3 Subject 4 0 0 0 0 0 0 1 2 Subject 5 1 1 1 1 1 1 2 3 Subject 6 0 0 0 0 0 0 2 3 Subject 7 2 2 2 2 2 2 3 3 Subject 8 0 0 0 0 0 1 2 3 P (vs. reference) — 1.00 1.00 0.99 0.94 0.74 <0.05 <0.01 Septum Subject 1 0 0 0 0 0 0 1 1 Subject 2 0 0 0 0 0 0 0 1 Subject 3 0 0 0 0 0 0 0 1 Subject 4 1 1 1 1 1 1 1 2 Subject 5 1 1 1 1 1 1 1 1 Subject 6 0 0 0 0 0 0 0 0 Subject 7 1 1 1 1 1 1 1 1 Subject 8 1 1 1 1 1 1 2 2 P (vs. reference) — 1.00 1.00 1.00 1.00 1.00 0.98 0.29 ↵* Data are erroneous-decrease scores based on 4-point scale (0 = none, 1 = mild, 2 = moderate, and 3 = severe).
Supplemental Data
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