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Research ArticleImaging

An Analysis of 3 Common CardioGen-82 82Rb Infusion System Injection Methods and Their Impact on Clinical Volume and Image Counts

Amanda E. Roby, Nils P. Johnson and K. Lance Gould
Journal of Nuclear Medicine Technology June 2015, 43 (2) 113-116; DOI: https://doi.org/10.2967/jnmt.114.152702
Amanda E. Roby
Weatherhead PET Center for Preventing and Reversing Atherosclerosis, University of Texas Medical School at Houston, Houston, Texas
PET, CNMT, ARRT
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Nils P. Johnson
Weatherhead PET Center for Preventing and Reversing Atherosclerosis, University of Texas Medical School at Houston, Houston, Texas
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K. Lance Gould
Weatherhead PET Center for Preventing and Reversing Atherosclerosis, University of Texas Medical School at Houston, Houston, Texas
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  • FIGURE 1.
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    FIGURE 1.

    Graph of average daily volume differences between each method for all 3 generators. Error bars represent SD for each infusion method. Generator 2 was used for 20 d and generator 3 for 15 d.

  • FIGURE 2.
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    FIGURE 2.

    Graph of average daily dose differences for each method across all 3 generators. Error bars represent SD for each infusion method. Generator 2 was used for 20 d and generator 3 for 15 d.

  • FIGURE 3.
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    FIGURE 3.

    Difference in counts per s (kcps) for each method for early-arterial and late-uptake acquisitions. (A) 2 min flow. (B) 5 min uptake.

  • FIGURE 4.
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    FIGURE 4.

    Total estimated volume use for each examination volume and QA simulation. (A) 204 examinations. (B) 180 examinations. (C) 138 examinations.

Tables

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    TABLE 1

    Vial Test Volume in Milliliters

    ProtocolGenerator 1, total volumeGenerator 2, total volumeGenerator 3, total volume
    Bolus744555436
    50 mL1,079843660
    30 mL854688504
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    TABLE 2

    Dose Ranges

    ProtocolGenerator 1Generator 2Generator 3
    50 mL987.9–1,665 (26.7–45)1,080.4–1,683.5 (29.2–45.5)1,143.3–1,631.7 (30.9–44.1)
    30 mL969.4–1,665 (26.2–45)1,069.3–1,665 (28.9–45)1,121.1–1,679.8 (30.3–45.4)
    Bolus913.9–1,665 (24.7–45)999–1,683.5 (27–45.5)958.3–1,631.7 (25.9–44.1)
    • Data are MBq, with mCi in parentheses.

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    TABLE 3

    Imaged Activity

    Scanner resultsEarly counts (2 min) (E+08)Dose (MBq [mCi])Late counts (90 s post) (E+08)Dose (MBq [mCi])
    50 mL5.61,121.1 (30.3)2.191,121.1 (30.3)
    30 mL4.41,076.7 (29.1)1.961,076.7 (29.1)
    Bolus2.8862.1 (23.3)1.37858.4 (23.2)
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Journal of Nuclear Medicine Technology: 43 (2)
Journal of Nuclear Medicine Technology
Vol. 43, Issue 2
June 1, 2015
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An Analysis of 3 Common CardioGen-82 82Rb Infusion System Injection Methods and Their Impact on Clinical Volume and Image Counts
Amanda E. Roby, Nils P. Johnson, K. Lance Gould
Journal of Nuclear Medicine Technology Jun 2015, 43 (2) 113-116; DOI: 10.2967/jnmt.114.152702

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An Analysis of 3 Common CardioGen-82 82Rb Infusion System Injection Methods and Their Impact on Clinical Volume and Image Counts
Amanda E. Roby, Nils P. Johnson, K. Lance Gould
Journal of Nuclear Medicine Technology Jun 2015, 43 (2) 113-116; DOI: 10.2967/jnmt.114.152702
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Keywords

  • 82Rb generator
  • elution volume
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  • 82Rb expiration
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